Melanoma Marker Antibody (PNL2): sc-59306

Melanoma Marker Antibody (PNL2) is a mouse monoclonal IgG1 antibody that detects Melanoma Marker in mouse and human samples through immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Melanoma Marker (PNL2) antibody is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. Melanoma Marker plays a crucial role in identifying and characterizing melanocytes, which are responsible for melanin production, the pigment that gives color to skin, hair, and eyes. Understanding Melanoma Marker is vital, as anti-Melanoma Marker antibody (PNL2) aids in diagnosing and treating malignant melanoma, a serious form of skin cancer that can arise from benign moles or de novo. Melanoma Marker expression is particularly important in distinguishing malignant melanomas from benign lesions, thereby guiding clinical decisions and therapeutic strategies. Epidemiological studies have linked ultraviolet radiation exposure to melanoma development, highlighting the need for effective diagnostic tools like Melanoma Marker monoclonal antibody (PNL2) to improve patient outcomes. The four most common types of melanoma include superficial spreading melanomas, nodular melanomas, acral lentiginous melanomas, and lentigo malignas, each with distinct characteristics and clinical implications, underscoring the importance of accurate detection and monitoring of melanocyte activity.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Melanoma Marker Antibody (PNL2) has 22 citations in a variety of scientific publications.

Primary antibodies like Anti-Melanoma Marker Antibody (PNL2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Melanoma Marker Antibody (PNL2) Specifications

Alternate Product Name: Melanoma Marker

Product Clone Name: PNL2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Melanoma Marker

Epitope Species: human

Product Reactivity/Detection: melanocytes

Species Reactivity/Detection: mouse, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 22 citations in various scientific publications

Available Conjugates/Forms for Melanoma Marker Antibody (PNL2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Melanoma Marker antibody is Melanoma Marker Antibody (HMB45): sc-59305.