Melanoma Marker Antibody (2G12): sc-69646

Melanoma Marker Antibody (2G12) is a mouse monoclonal IgG1 antibody that detects Melanoma Marker in human samples through applications such as western blotting (WB) and immunofluorescence (IF). Anti-Melanoma Marker antibody (2G12) plays a crucial role in the study of malignant melanoma, a serious form of skin cancer that arises from melanocytes, the pigment-producing cells responsible for melanin synthesis. Understanding the structure of Melanoma Marker is vital, as this protein is involved in critical cellular processes such as cell adhesion and migration, which are essential for the progression and metastasis of melanoma. Melanoma Marker′s structure includes specific domains that facilitate interactions with other cellular components, influencing signaling pathways that regulate cell growth and survival. By targeting these structural features, Melanoma Marker monoclonal antibody (2G12) provides valuable insights into the mechanisms underlying melanoma development and progression, making this research tool indispensable for investigating this aggressive cancer type.

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Melanoma Marker Antibody (2G12) References:

1. Tissue distribution and differential expression of melanocortin 1 receptor, a malignant melanoma marker.  |  Salazar-Onfray, F., et al. 2002. Br J Cancer. 87: 414-22. PMID: 12177778
2. Detection of mitochondrial DNA alterations in plasma of malignant melanoma patients.  |  Takeuchi, H., et al. 2004. Ann N Y Acad Sci. 1022: 50-4. PMID: 15251939
3. B16 melanoma secretomes and in vitro invasiveness: syntenin as an invasion modulator.  |  Rondepierre, F., et al. 2010. Melanoma Res. 20: 77-84. PMID: 20016392
4. Clear cell variant of diffuse large B-cell lymphoma: a case report.  |  Manxhuka-Kerliu, S., et al. 2011. J Med Case Rep. 5: 182. PMID: 21569513
5. L1CAM from human melanoma carries a novel type of N-glycan with Galβ1-4Galβ1- motif. Involvement of N-linked glycans in migratory and invasive behaviour of melanoma cells.  |  Hoja-Łukowicz, D., et al. 2013. Glycoconj J. 30: 205-25. PMID: 22544341
6. Breast carcinoma with positive results for melanoma marker (HMB-45). HMB-45 immunoreactivity in normal and neoplastic breast.  |  Bonetti, F., et al. 1989. Am J Clin Pathol. 92: 491-5. PMID: 2552794
7. Proteomics and Biochemical Analyses of Secreted Proteins Revealed a Novel Mechanism by Which ADAM12S Regulates the Migration of Gastric Cancer Cells.  |  Chang, Z., et al. 2022. J Proteome Res. 21: 2160-2172. PMID: 35926154
8. Esophageal carcinoma with SMARCA4 mutation: a narrative review for this rare entity.  |  Xu, J. and Chi, Z. 2024. Transl Gastroenterol Hepatol. 9: 24. PMID: 38716209
9. Three-dimensional cell spheroid culture and cell viability study of uveal melanoma cell line C918 with luteolin treatment.  |  Jinhai, Y., et al. 2024. Int Ophthalmol. 44: 385. PMID: 39306600
10. Cytodiagnosis of amelanotic metastatic malignant melanoma: an immunocytochemical study.  |  Gupta, RK. and Lallu, S. 1997. Diagn Cytopathol. 16: 238-41. PMID: 9099545

The preferred Melanoma Marker antibody is Melanoma Marker Antibody (HMB45): sc-59305.