Med30 Antibody (A-11): sc-374480
- Med30 Antibody (A-11) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 119-155 within an internal region of Med30 of human origin
- recommended for detection of Med30 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Med30 Antibody (A-11). This work is in progress.
Med30 Antibody (A-11) is a mouse monoclonal IgM antibody that detects Med30 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Med30 is a crucial subunit of the RNA polymerase II (Pol II) transcriptional mediator complex, which plays a vital role in the regulated transcription of Pol II-dependent genes. The complex acts as a bridge, facilitating communication between gene-specific regulatory proteins and the basal Pol II transcription machinery, thereby ensuring precise gene expression. Med30 is primarily located in the nucleus, where Med30 is essential for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors, highlighting Med30′s importance in the transcriptional regulation process. Med30 is expressed in various tissues, including the brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle, underscoring Med30′s widespread significance in cellular functions. Med30′s ability to interact with specific regulatory proteins further emphasizes Med30′s role in modulating gene expression, making anti-Med30 antibody (A-11) an invaluable tool for researchers studying transcriptional regulation and its implications in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Med30 Antibody (A-11) | sc-374480 | 200 µg/ml | $316.00 | |||
Med30 (A-11) Neutralizing Peptide | sc-374480 P | 100 µg/0.5 ml | $68.00 |