MDHC Antibody (28): sc-101516

MDHC Antibody (28) is a mouse monoclonal IgG1 antibody that detects malate dehydrogenase cytosolic (MDHC) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). MDHC is a crucial NAD-dependent enzyme that plays a significant role in glycometabolism by catalyzing the conversion of L-malate and NAD into oxaloacetate and NADH, which is vital for energy production in aerobic conditions. Anti-MDHC antibody (28) targets an enzyme predominantly expressed in tissues such as the brain, heart, and skeletal muscle, where MDHC supports essential functions including muscle contraction, neuronal signal transmission, and various metabolic pathways. MDHC operates as a homodimer and is highly conserved across different species, including plants, animals, and bacteria, highlighting its fundamental biological importance. MDHC activity is regulated by hormones such as the sesquiterpenoid juvenile hormone and the steroid hormone ecdysone, which underscores MDHC′s role in developmental processes and metabolic regulation. With an ability to facilitate critical biochemical reactions, MDHC is integral to maintaining cellular energy homeostasis and overall physiological function, making anti-MDHC antibody (28) an invaluable tool for researchers studying metabolic pathways and energy production mechanisms.

The preferred MDHC antibody is MDHC Antibody (H-6): sc-166879.