Anti-MAT Iα/IIα Antibody (B-10) is a mouse monoclonal IgG2b (kappa light chain) MAT Iα/IIα antibody provided at 200 µg/ml
raised against amino acids 1-300 mapping at the N-terminus of MAT IIα of human origin
Anti-MAT I alpha /II alpha Antibody (B-10) is recommended for detection of MAT Iα and MAT IIα of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-MAT I alpha /II alpha Antibody (B-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of MAT Iα/IIα (B-10): sc-166452.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
MAT Iα/IIα Antibody (B-10) is a high quality monoclonal MAT I alpha /II alpha antibody (also designated MAT Iα/IIα antibody) suitable for the detection of the MAT I alpha /II alpha protein of mouse, rat and human origin. MAT Iα/IIα Antibody (B-10) is available as both the non-conjugated anti-MAT I alpha /II alpha antibody form, as well as multiple conjugated forms of anti-MAT I alpha /II alpha antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Methionine adenosyltransferase (MAT) catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. Two different genes, MAT1A and MAT2A, encode a liver specific and non-liver specific form of MAT, respectively. Inactivation of the liver specific gene product, designated MAT I/III, associates with liver diseases such as cirrhosis. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NF-kB and TNFα cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences