MAP-2 Antibody (E-12): sc-74419
- MAP-2 Antibody (E-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 1-300 of MAP-2 of human origin
- recommended for detection of MAP-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See MAP-2 (A-4): sc-74421 for MAP-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MAP-2 Antibody (E-12). This work is in progress.
MAP-2 Antibody (E-12) is a mouse monoclonal IgG1 antibody that detects MAP-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MAP-2 is a crucial microtubule-associated protein that plays a significant role in stabilizing microtubules and facilitating their assembly, which is essential for maintaining the structural integrity of neurons and supporting intracellular transport. MAP-2 is predominantly located in the dendrites of neurons, where MAP-2 contributes to the formation of dendritic spines and the overall architecture of the neuronal cytoskeleton. This localization is vital for proper synaptic function and plasticity, as MAP-2 allows for the dynamic remodeling of the cytoskeleton in response to neuronal activity. Furthermore, MAP-2 is subject to various post-translational modifications, including phosphorylation, which can regulate MAP-2′s interaction with microtubules and other proteins, thereby influencing neuronal development and response to injury. MAP-2 (E-12) antibody is an invaluable tool for researchers studying the dynamics of microtubule organization and the role of MAP-2 in neurodevelopmental and neurodegenerative processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAP-2 Antibody (E-12) | sc-74419 | 200 µg/ml | $322.00 |