Date published: 2026-4-5

1-800-457-3801

SCBT Portrait Logo
Seach Input

MAP-2 Antibody (B-8): sc-74420

5.0(2)
Write a reviewAsk a question

Datasheets
  • MAP-2 Antibody (B-8) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
  • raised against amino acids 1-300 of MAP-2 of human origin
  • recommended for detection of MAP-2 of human origin by WB, IP, IF, IHC(P) and ELISA
  • See MAP-2 (A-4): sc-74421 for MAP-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for MAP-2 Antibody (B-8) for WB and IHC(P) applications. These reagents are now offered in bundles with MAP-2 Antibody (B-8) (see ordering information below).
Gene Editing Promo Banner

QUICK LINKS

SEE ALSO...

MAP-2 Antibody (B-8) is a mouse monoclonal IgG1 antibody that detects MAP-2 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). MAP-2 is a crucial microtubule-associated protein that plays a significant role in stabilizing microtubules and facilitating their assembly, which is essential for maintaining the structural integrity of neurons. Anti-MAP-2 antibody (B-8) recognizes protein predominantly located in the dendrites of neurons, where MAP-2 contributes to the organization of the cytoskeleton and supports the transport of organelles and signaling molecules. The proper localization and function of MAP-2 are vital for neuronal development and plasticity, as disruptions in MAP-2 expression or function can lead to neurodegenerative diseases and cognitive impairments. MAP-2 monoclonal antibody (B-8) provides reliable detection and analysis of MAP-2, enabling researchers to explore MAP-2′s role in cellular processes and implications in neurological disorders.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

MAP-2 Antibody (B-8)

sc-74420
200 µg/ml
$322.00

MAP-2 Antibody (B-8): m-IgG Fc BP-HRP Bundle

sc-539516
200 µg Ab; 10 µg BP
$361.00

MAP-2 Antibody (B-8): m-IgG1 BP-HRP Bundle

sc-541537
200 µg Ab; 20 µg BP
$361.00

How specific is the reactivity of this antibody for human MAP2 protein? And is there any data for cross-reactivity with mouse and rat tissue? Would like to use it to identify human xenograft in mouse spinal cord.

Asked by: xtensibleMlanguage
Thank you for your question. MAP-2 Antibody (B-8): sc-74420 is only recommended for detection of MAP-2 of human origin by WB, IP, IF, IHC(P) and ELISA. There is data for this antibody in murine cerebral cortices and there may be cross-reactivity with rat samples in different tissues as well.
Answered by: Tech Support Europe
Date published: 2021-01-13

Can MAP-2 (B-8): sc-74420 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Trav11
Thank you for your question. Yes, MAP-2 (B-8): sc-74420 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-28
  • y_2026, m_3, d_27, h_8CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_en_US, sid_74420, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 100ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Positive band in WB in IMRPositive band in WB in IMR-32 whole cell lysates. -SCBT QC
Date published: 2015-01-12
Rated 5 out of 5 by from Exceptional immunoperoxidase neuropil andExceptional immunoperoxidase neuropil and cytoplasmic staining in formalin fixed, paraffin-embedded human brain tissue. -SCBT QC
Date published: 2015-01-08
  • y_2026, m_3, d_27, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_en_US, sid_74420, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 10ms
  • REVIEWS, PRODUCT
MAP-2 Antibody (B-8) is rated 5.0 out of 5 by 2.
  • y_2026, m_3, d_27, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_en_US, sid_74420, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 98ms
  • REVIEWS, PRODUCT