MAO-A Antibody (G-10): sc-271123
- MAO-A Antibody (G-10) is a mouse monoclonal IgG1 κ MAO-A antibody, cited in 13 publications, provided at 200 µg/ml
- raised against amino acids 458-527 of MAO-A of human origin
- MAO-A Antibody (G-10) is recommended for detection of MAO-A of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-MAO-A Antibody (G-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for MAO-A Antibody (G-10) for WB and IHC(P) applications. These reagents are now offered in bundles with MAO-A Antibody (G-10) (see ordering information below).
MAO-A Antibody (G-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects MAO-A protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-MAO-A antibody (G-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Monoamine oxidase A (MAO-A) enzyme is located in the outer mitochondrial membrane and plays a crucial role in oxidative deamination of biogenic amines, which is essential for regulating neurotransmitter levels in the brain. Such regulation is particularly important as imbalances in neurotransmitter levels, such as serotonin and norepinephrine, have been linked to various psychiatric disorders, including depression and anxiety. Preferential degradation of serotonin by MAO-A highlights MAO-A′s significance in mood regulation and potential implications for therapeutic interventions targeting this enzyme. MAO-A and MAO-B genes are located on the X chromosome, which has led to research into their roles as genetic markers for psychiatric conditions, further emphasizing MAO-A′s function in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
MAO-A Antibody (G-10) References:
- Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: dissection of epigenetic and genetic factors. | Pinsonneault, JK., et al. 2006. Hum Mol Genet. 15: 2636-49. PMID: 16893905
- Deficient expression of monoamine oxidase A in the endometrium is associated with implantation failure in women participating as recipients in oocyte donation. | Henriquez, S., et al. 2006. Mol Hum Reprod. 12: 749-54. PMID: 17020906
- Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis. | Pchejetski, D., et al. 2007. Circ Res. 100: 41-9. PMID: 17158340
- The monoamine oxidase A (MAO-A) gene, family function and maltreatment as predictors of destructive behaviour during male adolescent alcohol consumption. | Nilsson, KW., et al. 2007. Addiction. 102: 389-98. PMID: 17298646
- A link between monoamine oxidase-A and apoptosis in serum deprived human SH-SY5Y neuroblastoma cells. | Fitzgerald, JC., et al. 2007. J Neural Transm (Vienna). 114: 807-10. PMID: 17393061
- Monoamine oxidase A gene polymorphism predicts adolescent outcome of attention-deficit/hyperactivity disorder. | Li, J., et al. 2007. Am J Med Genet B Neuropsychiatr Genet. 144B: 430-3. PMID: 17427196
- Localization of human monoamine oxidase-A gene to Xp11.23-11.4 by in situ hybridization: implications for Norrie disease. | Levy, ER., et al. 1989. Genomics. 5: 368-70. PMID: 2793188
- Reduced monoamine oxidase activity in platelets: a possible genetic marker for vulnerability to schizophrenia. | Wyatt, RJ., et al. 1973. Science. 179: 916-8. PMID: 4687789
- Properties of monoamine oxidase in control and Lesch-Nyhan fibroblasts. | Castro Costa, MR., et al. 1980. Biochem Genet. 18: 577-90. PMID: 7437013
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAO-A Antibody (G-10) | sc-271123 | 200 µg/ml | $322.00 | |||
MAO-A Antibody (G-10): m-IgG Fc BP-HRP Bundle | sc-529124 | 200 µg Ab; 10 µg BP | $361.00 | |||
MAO-A Antibody (G-10): m-IgGκ BP-HRP Bundle | sc-521852 | 200 µg Ab, 40 µg BP | $361.00 | |||
MAO-A Antibody (G-10): m-IgG1 BP-HRP Bundle | sc-543333 | 200 µg Ab; 20 µg BP | $361.00 | |||
MAO-A Antibody (G-10) AC | sc-271123 AC | 500 µg/ml, 25% agarose | $424.00 | |||
MAO-A Antibody (G-10) HRP | sc-271123 HRP | 200 µg/ml | $322.00 | |||
MAO-A Antibody (G-10) FITC | sc-271123 FITC | 200 µg/ml | $336.00 | |||
MAO-A Antibody (G-10) PE | sc-271123 PE | 200 µg/ml | $349.00 | |||
MAO-A Antibody (G-10) Alexa Fluor® 488 | sc-271123 AF488 | 200 µg/ml | $364.00 | |||
MAO-A Antibody (G-10) Alexa Fluor® 546 | sc-271123 AF546 | 200 µg/ml | $364.00 | |||
MAO-A Antibody (G-10) Alexa Fluor® 594 | sc-271123 AF594 | 200 µg/ml | $364.00 | |||
MAO-A Antibody (G-10) Alexa Fluor® 647 | sc-271123 AF647 | 200 µg/ml | $364.00 | |||
MAO-A Antibody (G-10) Alexa Fluor® 680 | sc-271123 AF680 | 200 µg/ml | $364.00 | |||
MAO-A Antibody (G-10) Alexa Fluor® 790 | sc-271123 AF790 | 200 µg/ml | $364.00 |