


Lyl-1 Antibody (F-3) is a mouse monoclonal IgG2a antibody that detects Lyl-1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Lyl-1, also known as lymphoblastic leukemia-derived sequence 1, is a crucial nuclear protein that plays a significant role in the regulation of hematopoiesis and is particularly important in the context of T cell acute lymphoblastic leukemia (T-ALL). Lyl-1 exists in complex with E2α proteins, forming heterodimeric complexes that exhibit unique DNA-binding properties, which are essential for the transcriptional regulation of genes involved in lymphocyte development. The interaction between Lyl-1 and E2α proteins is vital for maintaining proper hematopoietic function, and dysregulation of this complex can lead to chromosomal aberrations associated with T-ALL. Anti-Lyl-1 antibody (F-3) enables researchers to effectively study Lyl-1 expression and function in various cellular contexts, providing insights into its role in leukemia and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lyl-1 Antibody (F-3) | sc-374165 | 200 µg/ml | $322.00 | |||
Lyl-1 Antibody (F-3): m-IgGκ BP-HRP Bundle | sc-535399 | 200 µg Ab; 40 µg BP | $361.00 | |||
Lyl-1 Antibody (F-3): m-IgG2a BP-HRP Bundle | sc-546227 | 200 µg Ab; 10 µg BP | $361.00 | |||
Lyl-1 Antibody (F-3) X | sc-374165 X | 200 µg/0.1 ml | $322.00 |