LRP1 Antibody (A2MRα-2): sc-19616

LRP1 Antibody (A2MRα-2) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1), also known as α2-Macroglobulin Receptor (α2MR). LRP1 is a critical endocytic receptor involved in the internalization of over fifteen ligands, including α2-Macroglobulin and apolipoprotein E (apoE), which are essential for lipid metabolism, protease clearance, and cellular signaling pathways. This multifunctional protein is predominantly expressed in the brain, liver, and lungs, and plays a significant role in maintaining cellular homeostasis. Importantly, LRP1 is implicated in the pathogenesis of Alzheimer′s disease, underscoring its importance in neurological health and disease mechanisms. LRP1 mouse monoclonal antibody (A2MRα-2) is raised against human LRP1 purified from placental tissue. LRP1 monoclonal antibody (A2MRα-2) is recommended for applications like immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). LRP1 monoclonal antibody (A2MRα-2) supports advanced studies into LRP1′s diverse biological functions and involvement in critical physiological and pathological processes. LRP1 monoclonal antibody (A2MRα-2) is useful for researchers aiming to elucidate the complex roles of LRP1 in human health.

The preferred LRP1 antibody is LRP1 Antibody (8G1): sc-57353.