Liprin β2 Antibody (H-6): sc-376444

Liprin β2 Antibody (H-6) is a mouse monoclonal IgG1 antibody that detects Liprin β2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Liprin β2 plays a crucial role in cellular signaling and organization, particularly in axon guidance and mammary gland development, by serving as a scaffold that facilitates recruitment and anchoring of leukocyte common antigen-related (LAR) family phosphatases. This interaction is vital for proper neuronal development and function, as well as for regulation of cellular processes in various tissues. Liprin β2 is predominantly expressed in liver, kidney, intestine, heart, lung, and testis, with lower expression levels in brain and thymus, highlighting importance in both developmental and physiological contexts. Liprin β2 exists in four isoforms due to alternative splicing, with Isoform 1 representing full-length protein, while other isoforms exhibit specific deletions or alternative sequences that may influence functional roles. Anti-Liprin β2 antibody (H-6) is an essential tool for researchers investigating dynamics of LAR phosphatases and implications in health and disease.

The preferred Liprin β2 antibody is Liprin β2 Antibody (H-4): sc-514253.