Liprin β2 Antibody (A-6): sc-376493

Liprin β2 Antibody (A-6) is a mouse monoclonal IgG2b antibody that detects Liprin β2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Liprin β2 plays a crucial role in cellular signaling and organization, particularly in axon guidance and mammary gland development, by interacting with members of the leukocyte common antigen-related family of transmembrane protein tyrosine phosphatases. This interaction is vital for forming complex structures that serve as scaffolds, facilitating the recruitment and anchoring of LAR phosphatases, which are essential for proper neuronal development and function. Liprin β2 is predominantly expressed in the liver, kidney, intestine, heart, lung, and testis, with lower expression levels in the brain and thymus, highlighting its importance in various physiological processes. Notably, Liprin β2 exists in four isoforms due to alternative splicing, with Isoform 1 representing the full-length protein, while other isoforms exhibit specific deletions or alternative sequences that may influence their functional roles in cellular processes. Anti-Liprin β2 antibody (A-6) is an invaluable tool for researchers studying the intricate mechanisms of cell signaling and development, providing insights into molecular pathways that govern these critical biological functions.

The preferred Liprin β2 antibody is Liprin β2 Antibody (H-4): sc-514253.