LHPP Antibody (H-2): sc-376527

LHPP Antibody (H-2) is a mouse monoclonal IgG1 antibody that detects LHPP (phospholysine phosphohistidine inorganic pyrophosphate phosphatase) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LHPP is a 270 amino acid protein that functions as a homodimer and belongs to the HAD-like hydrolase superfamily, playing a crucial role in regulating phospholysine and phosphohistidine levels within cells. This regulation impacts various cellular processes, including signal transduction and metabolic pathways, which are essential for maintaining cellular homeostasis and function. LHPP is predominantly expressed in the liver and kidney, with moderate expression in the brain, highlighting its importance in metabolic regulation and potential implications in neurological health. The LHPP gene is located on chromosome 10, a region associated with several genetic disorders, underscoring LHPP′s relevance in both health and disease. With versatile applications and a critical role in cellular function, anti-LHPP antibody (H-2) serves as an invaluable tool for researchers studying phosphatase activity mechanisms and their implications in various biological contexts.

The preferred LHPP antibody is LHPP Antibody (B-2): sc-376648.