LDLR Antibody (F-7): sc-373830
- LDLR Antibody (F-7) is a mouse monoclonal IgG2a κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 13-47 near the N-terminus of LDLR of human origin
- recommended for detection of LDLR of human origin by WB, IP, IF and ELISA
- See LDLR (C7): sc-18823 for LDLR antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for LDLR Antibody (F-7) for WB applications. These reagents are now offered in bundles with LDLR Antibody (F-7) (see ordering information below).
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SEE ALSO...
LDLR Antibody (F-7) is a mouse monoclonal IgG2a antibody that detects low density lipoprotein receptor (LDLR) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-LDLR antibody (F-7) plays a crucial role in understanding LDLR function, which is essential for mediating low density lipoprotein (LDL) uptake and subsequent degradation in lysosomes, thereby providing necessary cholesterol to cells. LDLR (F-7) monoclonal antibody supports research into proper LDLR functioning, which is vital for maintaining cholesterol homeostasis, as dysfunction can lead to serious health issues, such as familial hypercholesterolemia (FH), a genetic disorder characterized by high cholesterol levels and increased risk of coronary atherosclerosis. LDLR protein is located on the cell surface as a transmembrane protein, where clustering in coated pits facilitates rapid endocytosis of bound LDL. This mechanism underscores LDLR importance in lipid metabolism and cardiovascular health, making LDLR (F-7) antibody an invaluable tool for researchers studying cholesterol regulation and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LDLR Antibody (F-7) | sc-373830 | 200 µg/ml | $316.00 | |||
LDLR Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-540403 | 200 µg Ab; 10 µg BP | $354.00 | |||
LDLR Antibody (F-7): m-IgG2a BP-HRP Bundle | sc-546903 | 200 µg Ab; 10 µg BP | $354.00 |