LCMT1 Antibody (F-4): sc-365063
- LCMT1 Antibody (F-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 179-334 mapping at the C-terminus of LCMT1 of human origin
- recommended for detection of LCMT1 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for LCMT1 Antibody (F-4) for WB applications. These reagents are now offered in bundles with LCMT1 Antibody (F-4) (see ordering information below).
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SEE ALSO...
LCMT1 Antibody (F-4) is a mouse monoclonal IgG1 antibody that detects LCMT1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LCMT1, or leucine carboxyl methyltransferase 1, is a crucial enzyme consisting of 334 amino acids that plays a significant role in the regulation of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in cell growth and proliferation. LCMT1 catalyzes the methylation of the carboxy group on the C-terminal leucine of the PP2A catalytic subunit (PP2Aα), thereby influencing PP2A activity and downstream effects on mitotic progression and cell survival. LCMT1-mediated regulation of PP2A is vital for maintaining cellular homeostasis, and dysregulation of this pathway has been implicated in tumor progression. LCMT1 exists in two isoforms due to alternative splicing, which may contribute to functional diversity and regulatory mechanisms within cells. Anti-LCMT1 antibody (F-4) serves as an essential tool for researchers studying the intricate roles of methylation in cellular processes and cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LCMT1 Antibody (F-4) | sc-365063 | 200 µg/ml | $322.00 | |||
LCMT1 Antibody (F-4): m-IgG Fc BP-HRP Bundle | sc-540305 | 200 µg Ab; 10 µg BP | $361.00 | |||
LCMT1 Antibody (F-4): m-IgG1 BP-HRP Bundle | sc-542027 | 200 µg Ab; 20 µg BP | $361.00 |