LCMT1 Antibody (C-8): sc-365064
- LCMT1 Antibody (C-8) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 179-334 mapping at the C-terminus of LCMT1 of human origin
- recommended for detection of LCMT1 of human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for LCMT1 Antibody (C-8) for WB applications. This reagent is now offered in a bundle with LCMT1 Antibody (C-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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LCMT1 Antibody (C-8) is a mouse monoclonal IgG2a antibody that detects LCMT1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LCMT1, or leucine carboxyl methyltransferase 1, is a crucial enzyme consisting of 334 amino acids that plays a significant role in the regulation of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in cell growth and proliferation. Anti-LCMT1 antibody (C-8) catalyzes the methylation of the carboxy group on the C-terminal leucine of the PP2A catalytic subunit (PP2Aα), a modification essential for proper PP2A functioning. This regulation is vital for normal mitotic progression and overall cell survival, highlighting LCMT1′s importance in cellular processes. LCMT1 exists in two isoforms due to alternative splicing, which may contribute to functional diversity and regulatory mechanisms. LCMT1 (C-8) antibody enables researchers to gain insights into LCMT1 and PP2A roles in various biological contexts, including implications in tumor progression and cell cycle regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LCMT1 Antibody (C-8) | sc-365064 | 200 µg/ml | $322.00 | |||
LCMT1 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-535143 | 200 µg Ab; 40 µg BP | $361.00 |