LAMP-2 Antibody (ABL-93): sc-20004
- LAMP-2 Antibody (ABL-93) is a rat monoclonal IgG2a, cited in 43 publications, provided at 200 µg/ml
- raised against glycoprotein fractions purified from BALB/c mouse embryo 3T3 cell line
- Anti-LAMP-2 Antibody (ABL-93) is recommended for detection of LAMP-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-LAMP-2 Antibody (ABL-93) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 405 for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LAMP-2 Antibody (ABL-93). This work is in progress.
QUICK LINKS
LAMP-2 Antibody (ABL-93) is a rat monoclonal IgG2a antibody raised against glycoprotein fractions purified from the BALB/c mouse embryo 3T3 cell line, with reactivity in mouse, rat, and human species. Anti-LAMP-2 antibody (ABL-93) is validated for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). LAMP-2, also known as CD107B, is a lysosome-associated membrane glycoprotein that plays a crucial role in lysosomal function and cellular homeostasis. LAMP-2 is a type I transmembrane protein that helps maintain lysosomal integrity, acidity, and protects lysosomal membranes from degradation. LAMP-2 is also involved in autophagy, mediating the fusion of autophagosomes with lysosomes, which is essential for the degradation and recycling of cellular components. Dysregulation of LAMP-2 is implicated in lysosomal storage disorders, such as Danon disease, and may contribute to altered lysosomal function in cancer and other diseases. LAMP-2 is sorted at the trans-Golgi network and trafficked intracellularly, highlighting its role in cellular transport and lysosomal biogenesis. LAMP-2 monoclonal antibody (ABL-93) is a valuable tool for studying LAMP-2′s function in lysosomal maintenance, autophagy, and disease processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LAMP-2 Antibody (ABL-93) | sc-20004 | 200 µg/ml | $322.00 | |||
LAMP-2 Antibody (ABL-93) AC | sc-20004 AC | 500 µg/ml, 25% agarose | $424.00 | |||
LAMP-2 Antibody (ABL-93) HRP | sc-20004 HRP | 200 µg/ml | $322.00 | |||
LAMP-2 Antibody (ABL-93) FITC | sc-20004 FITC | 200 µg/ml | $336.00 | |||
LAMP-2 Antibody (ABL-93) PE | sc-20004 PE | 200 µg/ml | $349.00 | |||
LAMP-2 Antibody (ABL-93) Alexa Fluor® 488 | sc-20004 AF488 | 200 µg/ml | $364.00 | |||
LAMP-2 Antibody (ABL-93) Alexa Fluor® 546 | sc-20004 AF546 | 200 µg/ml | $364.00 | |||
LAMP-2 Antibody (ABL-93) Alexa Fluor® 594 | sc-20004 AF594 | 200 µg/ml | $364.00 | |||
LAMP-2 Antibody (ABL-93) Alexa Fluor® 647 | sc-20004 AF647 | 200 µg/ml | $364.00 | |||
LAMP-2 Antibody (ABL-93) Alexa Fluor® 680 | sc-20004 AF680 | 200 µg/ml | $364.00 | |||
LAMP-2 Antibody (ABL-93) Alexa Fluor® 790 | sc-20004 AF790 | 200 µg/ml | $364.00 | |||
LAMP-2 Antibody (ABL-93) Alexa Fluor® 405 | sc-20004 AF405 | 200 µg/ml | $364.00 |