LAMP1 Antibody (4E151): sc-71489
- LAMP1 Antibody (4E151) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- raised against LAMP-1 of rat origin
- recommended for detection of LAMP-1 of mouse and rat origin by WB, IP and IF
- See LAMP1 (H4A3): sc-20011 for LAMP1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for LAMP1 Antibody (4E151) for WB applications. These reagents are now offered in bundles with LAMP1 Antibody (4E151) (see ordering information below).
LAMP-1 Antibody (4E151) is a mouse monoclonal IgG1 antibody that detects LAMP-1 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). LAMP-1, also known as CD107a, is a glycosylated type I membrane protein that plays a crucial role in maintaining lysosomal function and integrity. LAMP-1 is primarily located on the surface of lysosomes and is essential for proper functioning of these organelles, which are responsible for degrading and recycling cellular waste. LAMP-1 on the lysosomal membrane is vital for protecting lysosomes from autodigestion, as LAMP-1 helps maintain the acidic environment necessary for enzymatic activity. Additionally, LAMP-1 is expressed on the surface of thrombin-activated platelets, contributing to their adhesive and prothrombic properties, which is particularly important in the context of hemostasis and wound healing. LAMP-1 expression levels are notably increased in patients with lysosomal storage disorders, highlighting LAMP-1′s significance in cellular health and disease. With insights into lysosomal function and pathology, anti-LAMP-1 antibody (4E151) serves as an invaluable tool for researchers studying cellular processes and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LAMP1 Antibody (4E151) | sc-71489 | 200 µg/ml | $322.00 | |||
LAMP1 Antibody (4E151): m-IgG Fc BP-HRP Bundle | sc-539371 | 200 µg Ab; 10 µg BP | $361.00 | |||
LAMP1 Antibody (4E151): m-IgG1 BP-HRP Bundle | sc-541442 | 200 µg Ab; 20 µg BP | $361.00 |