Lamin A Antibody (C-3): sc-518013
- Lamin A Antibody (C-3) is a mouse monoclonal IgG2b κ, cited in 16 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 580-601 near the C-terminus of Lamin A of human origin
- Anti-Lamin A Antibody (C-3) is recommended for detection of Lamin A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Lamin A Antibody (C-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Lamin A Antibody (C-3). This work is in progress.
QUICK LINKS
Lamin A Antibody (C-3) is a mouse monoclonal IgG2b kappa light chain antibody designed to detect Lamin A, also known as LMNA or A-type lamin, across multiple species including mouse, rat, and human. Lamin A is a critical component of the nuclear lamina, providing structural support to the nuclear envelope and playing a vital role in maintaining nuclear integrity and cellular morphology. Lamin A undergoes essential post-translational modifications, including farnesylation, endoproteolytic cleavage, and methylation, which are crucial for proper localization and function within the nucleus. Lamin A is involved in regulating key cellular processes such as DNA replication, transcription, and the cell cycle, making Lamin A indispensable for cellular longevity and stability. Lamin A (C-3) monoclonal antibody targets the amino acids 580-601 near the C-terminus of human Lamin A. Anti-Lamin A antibody (C-3) is versatile for use in various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA), providing reliable and consistent results for researchers studying nuclear structure, gene expression regulation, and laminopathies. Anti-Lamin A antibody (C-3) facilitates advancements in understanding the molecular mechanisms underlying a range of diseases linked to LMNA mutations.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lamin A Antibody (C-3) | sc-518013 | 200 µg/ml | $322.00 | |||
Lamin A Antibody (C-3) AC | sc-518013 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Lamin A Antibody (C-3) HRP | sc-518013 HRP | 200 µg/ml | $322.00 | |||
Lamin A Antibody (C-3) FITC | sc-518013 FITC | 200 µg/ml | $336.00 | |||
Lamin A Antibody (C-3) PE | sc-518013 PE | 200 µg/ml | $349.00 | |||
Lamin A Antibody (C-3) Alexa Fluor® 488 | sc-518013 AF488 | 200 µg/ml | $364.00 | |||
Lamin A Antibody (C-3) Alexa Fluor® 546 | sc-518013 AF546 | 200 µg/ml | $364.00 | |||
Lamin A Antibody (C-3) Alexa Fluor® 594 | sc-518013 AF594 | 200 µg/ml | $364.00 | |||
Lamin A Antibody (C-3) Alexa Fluor® 647 | sc-518013 AF647 | 200 µg/ml | $364.00 | |||
Lamin A Antibody (C-3) Alexa Fluor® 680 | sc-518013 AF680 | 200 µg/ml | $364.00 | |||
Lamin A Antibody (C-3) Alexa Fluor® 790 | sc-518013 AF790 | 200 µg/ml | $364.00 |