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L-type Ca++ CP β3 Antibody (E-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects L-type Ca++ CP beta 3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-L-type Ca++ CP beta 3 antibody (E-10) is available as non-conjugated format. L-type Ca++ CP beta 3 protein, also known as CACNB3, plays a crucial role in voltage-dependent calcium channels′ function, vital for neurotransmitter release and muscle contraction. CACNB3 consists of 484 amino acids and features one SH3 domain, with expression in tissues including ovary, brain, and smooth muscle. L-type Ca++ CP β3 is essential for modulating calcium currents and membrane trafficking of the α1 subunit, influencing overall calcium channel activity. L-type Ca++ CP β3 (E-10) antibody enhances peak calcium current and alters voltage dependencies of activation and inactivation, critical for proper cellular signaling. Two isoforms of L-type Ca++ CP β3 arise from alternative splicing, contributing to calcium channels′ functional diversity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-type Ca++ CP β3 Antibody (E-10) | sc-398995 | 200 µg/ml | $322.00 | |||
L-type Ca++ CP β3 Antibody (E-10): m-IgG Fc BP-HRP Bundle | sc-538565 | 200 µg Ab; 10 µg BP | $361.00 | |||
L-type Ca++ CP β3 Antibody (E-10): m-IgGκ BP-HRP Bundle | sc-536203 | 200 µg Ab; 40 µg BP | $361.00 | |||
L-type Ca++ CP β3 Antibody (E-10): m-IgG1 BP-HRP Bundle | sc-545770 | 200 µg Ab; 20 µg BP | $361.00 |