KV3.2 Antibody (H-11): sc-514099
- KV3.2 Antibody (H-11) is a mouse monoclonal IgG1 κ KV3.2 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 168-215 mapping within an internal region of KV3.2 of human origin
- KV3.2 Antibody (H-11) is recommended for detection of KV3.2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-KV3.2 Antibody (H-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KV3.2 Antibody (H-11) for WB applications. These reagents are now offered in bundles with KV3.2 Antibody (H-11) (see ordering information below).
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KV3.2 Antibody (H-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects KV3.2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KV3.2 (H-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. KV3.2 protein plays a crucial role in regulating voltage-dependent potassium ion permeability in excitable membranes, essential for proper repolarization of action potentials in neurons and muscle cells. KV3.2 protein belongs to the voltage-gated potassium (KV) channel family, which consists of over 30 different proteins forming potassium channel subunits. These channels maintain cellular electrical excitability, and dysfunction can lead to various neurological and cardiac disorders. KV3.2 protein features a multipass membrane structure, forming tetramers with other KV subunits to influence channel gating and permeation properties. KV3.2 protein′s unique tail may play a significant role in targeting channels to specific subcellular compartments, critical for regulatory functions and overall cellular signaling.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
KV3.2 Antibody (H-11) References:
- Region-specific expression of a K+ channel gene in brain. | Rudy, B., et al. 1992. Proc Natl Acad Sci U S A. 89: 4603-7. PMID: 1374908
- Potassium channel subunit Kv3.2 and the water channel aquaporin-4 are selectively localized to cerebellar pinceau. | Bobik, M., et al. 2004. Brain Res. 1026: 168-78. PMID: 15488478
- Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels. | Yan, L., et al. 2005. Mol Pharmacol. 67: 1513-21. PMID: 15709110
- Modulation of Kv3 subfamily potassium currents by the sea anemone toxin BDS: significance for CNS and biophysical studies. | Yeung, SY., et al. 2005. J Neurosci. 25: 8735-45. PMID: 16177043
- Differential expression of Kv3.1b and Kv3.2 potassium channel subunits in interneurons of the basolateral amygdala. | McDonald, AJ. and Mascagni, F. 2006. Neuroscience. 138: 537-47. PMID: 16413129
- Developmental changes in the expression of calbindin and potassium-channel subunits Kv3.1b and Kv3.2 in mouse Renshaw cells. | Song, ZM., et al. 2006. Neuroscience. 139: 531-8. PMID: 16460880
- Shaw-like rat brain potassium channel cDNA's with divergent 3' ends. | Luneau, C., et al. 1991. FEBS Lett. 288: 163-7. PMID: 1879548
- Molecular cloning of a member of a third class of Shaker-family K+ channel genes in mammals. | McCormack, T., et al. 1990. Proc Natl Acad Sci U S A. 87: 5227-31. PMID: 2367536
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KV3.2 Antibody (H-11) | sc-514099 | 200 µg/ml | $322.00 | |||
KV3.2 Antibody (H-11): m-IgG Fc BP-HRP Bundle | sc-531030 | 200 µg Ab; 10 µg BP | $361.00 | |||
KV3.2 Antibody (H-11): m-IgGκ BP-HRP Bundle | sc-524605 | 200 µg Ab, 40 µg BP | $361.00 | |||
KV3.2 Antibody (H-11): m-IgG1 BP-HRP Bundle | sc-544366 | 200 µg Ab; 20 µg BP | $361.00 | |||
KV3.2 Antibody (H-11) AC | sc-514099 AC | 500 µg/ml, 25% agarose | $424.00 | |||
KV3.2 Antibody (H-11) HRP | sc-514099 HRP | 200 µg/ml | $322.00 | |||
KV3.2 Antibody (H-11) FITC | sc-514099 FITC | 200 µg/ml | $336.00 | |||
KV3.2 Antibody (H-11) PE | sc-514099 PE | 200 µg/ml | $349.00 | |||
KV3.2 Antibody (H-11) Alexa Fluor® 488 | sc-514099 AF488 | 200 µg/ml | $364.00 | |||
KV3.2 Antibody (H-11) Alexa Fluor® 546 | sc-514099 AF546 | 200 µg/ml | $364.00 | |||
KV3.2 Antibody (H-11) Alexa Fluor® 594 | sc-514099 AF594 | 200 µg/ml | $364.00 | |||
KV3.2 Antibody (H-11) Alexa Fluor® 647 | sc-514099 AF647 | 200 µg/ml | $364.00 | |||
KV3.2 Antibody (H-11) Alexa Fluor® 680 | sc-514099 AF680 | 200 µg/ml | $364.00 | |||
KV3.2 Antibody (H-11) Alexa Fluor® 790 | sc-514099 AF790 | 200 µg/ml | $364.00 |