KIF2A Antibody (D-7): sc-271471
- KIF2A Antibody (D-7) is a mouse monoclonal IgG1 κ KIF2A antibody, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 528-569 near the C-terminus of KIF2A of human origin
- KIF2A Antibody (D-7) is recommended for detection of KIF2A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-KIF2A Antibody (D-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KIF2A Antibody (D-7) for WB applications. These reagents are now offered in bundles with KIF2A Antibody (D-7) (see ordering information below).
KIF2A Antibody (D-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects KIF2A of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KIF2A Antibody (D-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Kinesin heavy chain member 2A (KIF2A), also known as KNS2, is a crucial microtubule-associated motor protein that plays a significant role in axonal transport and cell division. KIF2A is primarily located in developing axons, where KIF2A facilitates the transport of essential vesicles, macromolecules, and membranous organelles along microtubules, thereby supporting neuronal function and development. Proper functioning of KIF2A is vital for maintaining neuronal integrity and overall health of the nervous system. KIF2A is regulated by the synthetic retinoid N-(4-hydroxyphenyl)-all-trans-retinamide, which has been shown to induce apoptotic cell death in vitro and acts as a cancer chemopreventive agent in vivo. KIF2A′s ability to interact with various cellular components underscores KIF2A′s importance in cellular dynamics and highlights KIF2A′s potential as a therapeutic target in neurodegenerative diseases and cancer.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
KIF2A Antibody (D-7) References:
- Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. | Homma, N., et al. 2003. Cell. 114: 229-39. PMID: 12887924
- Kinesin superfamily proteins and their various functions and dynamics. | Hirokawa, N. and Takemura, R. 2004. Exp Cell Res. 301: 50-9. PMID: 15501445
- Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique. | Debernardi, S., et al. 1997. Genomics. 42: 67-73. PMID: 9177777
- Suppression of KIF2 in PC12 cells alters the distribution of a growth cone nonsynaptic membrane receptor and inhibits neurite extension. | Morfini, G., et al. 1997. J Cell Biol. 138: 657-69. PMID: 9245793
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KIF2A Antibody (D-7) | sc-271471 | 200 µg/ml | $316.00 | |||
KIF2A Antibody (D-7): m-IgG Fc BP-HRP Bundle | sc-529191 | 200 µg Ab; 10 µg BP | $354.00 | |||
KIF2A Antibody (D-7): m-IgGκ BP-HRP Bundle | sc-521952 | 200 µg Ab, 40 µg BP | $354.00 | |||
KIF2A Antibody (D-7): m-IgG1 BP-HRP Bundle | sc-543378 | 200 µg Ab; 20 µg BP | $354.00 | |||
KIF2A Antibody (D-7) AC | sc-271471 AC | 500 µg/ml, 25% agarose | $416.00 | |||
KIF2A Antibody (D-7) HRP | sc-271471 HRP | 200 µg/ml | $316.00 | |||
KIF2A Antibody (D-7) FITC | sc-271471 FITC | 200 µg/ml | $330.00 | |||
KIF2A Antibody (D-7) PE | sc-271471 PE | 200 µg/ml | $343.00 | |||
KIF2A Antibody (D-7) Alexa Fluor® 488 | sc-271471 AF488 | 200 µg/ml | $357.00 | |||
KIF2A Antibody (D-7) Alexa Fluor® 546 | sc-271471 AF546 | 200 µg/ml | $357.00 | |||
KIF2A Antibody (D-7) Alexa Fluor® 594 | sc-271471 AF594 | 200 µg/ml | $357.00 | |||
KIF2A Antibody (D-7) Alexa Fluor® 647 | sc-271471 AF647 | 200 µg/ml | $357.00 | |||
KIF2A Antibody (D-7) Alexa Fluor® 680 | sc-271471 AF680 | 200 µg/ml | $357.00 | |||
KIF2A Antibody (D-7) Alexa Fluor® 790 | sc-271471 AF790 | 200 µg/ml | $357.00 | |||
KIF2A (D-7) Neutralizing Peptide | sc-271471 P | 100 µg/0.5 ml | $68.00 |