KIF16B Antibody (H-6): sc-390309
- KIF16B Antibody (H-6) is a mouse monoclonal IgG1 κ KIF16B antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-270 mapping at the N-terminus of KIF16B of human origin
- KIF16B Antibody (H-6) is recommended for detection of KIF16B of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-KIF16B Antibody (H-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KIF16B Antibody (H-6) for WB applications. These reagents are now offered in bundles with KIF16B Antibody (H-6) (see ordering information below).
KIF16B Antibody (H-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects KIF16B protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-KIF16B antibody (H-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. KIF16B, also known as kinesin family member 16B or sorting nexin-23, is a 1,317 amino acid protein characterized by the presence of one forkhead-associated domain, one kinesin motor domain, and one phosphoinositide-binding PX domain, which are essential for its function as a microtubule-dependent motor protein. This protein is primarily located in early endosomes at the ends of microtubules, where KIF16B plays a critical role in regulating the motility of these organelles, thus influencing the balance between endosomal recycling and degradation. Proper functioning of KIF16B is vital for maintaining cellular homeostasis, as KIF16B facilitates the transport of various cellular components, including organelles and vesicles, which are crucial for processes such as cell division and membrane trafficking. Notably, KIF16B is subject to alternative splicing, resulting in the expression of five distinct isoforms, each potentially contributing to diverse functional roles within the cell.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
KIF16B Antibody (H-6) References:
- A large family of endosome-localized proteins related to sorting nexin 1. | Teasdale, RD., et al. 2001. Biochem J. 358: 7-16. PMID: 11485546
- Sorting out the cellular functions of sorting nexins. | Worby, CA. and Dixon, JE. 2002. Nat Rev Mol Cell Biol. 3: 919-31. PMID: 12461558
- Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. | Hoepfner, S., et al. 2005. Cell. 121: 437-50. PMID: 15882625
- Analysis of the kinesin superfamily: insights into structure and function. | Miki, H., et al. 2005. Trends Cell Biol. 15: 467-76. PMID: 16084724
- The Phox (PX) domain proteins and membrane traffic. | Seet, LF. and Hong, W. 2006. Biochim Biophys Acta. 1761: 878-96. PMID: 16782399
- The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. | Vasilescu, J., et al. 2007. J Proteome Res. 6: 298-305. PMID: 17203973
- The structural basis of novel endosome anchoring activity of KIF16B kinesin. | Blatner, NR., et al. 2007. EMBO J. 26: 3709-19. PMID: 17641687
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KIF16B Antibody (H-6) | sc-390309 | 200 µg/ml | $322.00 | |||
KIF16B Antibody (H-6): m-IgG Fc BP-HRP Bundle | sc-530124 | 200 µg Ab; 10 µg BP | $361.00 | |||
KIF16B Antibody (H-6): m-IgGκ BP-HRP Bundle | sc-523485 | 200 µg Ab, 40 µg BP | $361.00 | |||
KIF16B Antibody (H-6) AC | sc-390309 AC | 500 µg/ml, 25% agarose | $424.00 | |||
KIF16B Antibody (H-6) HRP | sc-390309 HRP | 200 µg/ml | $322.00 | |||
KIF16B Antibody (H-6) FITC | sc-390309 FITC | 200 µg/ml | $336.00 | |||
KIF16B Antibody (H-6) PE | sc-390309 PE | 200 µg/ml | $349.00 | |||
KIF16B Antibody (H-6) Alexa Fluor® 488 | sc-390309 AF488 | 200 µg/ml | $364.00 | |||
KIF16B Antibody (H-6) Alexa Fluor® 546 | sc-390309 AF546 | 200 µg/ml | $364.00 | |||
KIF16B Antibody (H-6) Alexa Fluor® 594 | sc-390309 AF594 | 200 µg/ml | $364.00 | |||
KIF16B Antibody (H-6) Alexa Fluor® 647 | sc-390309 AF647 | 200 µg/ml | $364.00 | |||
KIF16B Antibody (H-6) Alexa Fluor® 680 | sc-390309 AF680 | 200 µg/ml | $364.00 | |||
KIF16B Antibody (H-6) Alexa Fluor® 790 | sc-390309 AF790 | 200 µg/ml | $364.00 |