KCTD12 Antibody (F-6): sc-271855
- KCTD12 Antibody (F-6) is a mouse monoclonal IgG1 κ KCTD12 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 117-137 within an internal region of KCTD12 of human origin
- KCTD12 Antibody (F-6) is recommended for detection of KCTD12 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
- Anti-KCTD12 Antibody (F-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for KCTD12 Antibody (F-6) for WB applications. These reagents are now offered in bundles with KCTD12 Antibody (F-6) (see ordering information below).
KCTD12 Antibody (F-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects KCTD12 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KCTD12 (F-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. KCTD12, also known as potassium channel tetramerisation domain containing 12, is a 325 amino acid protein predominantly expressed in fetal organs, with highest expression levels found in the cochlea and brain, while showing minimal presence in adult tissues such as the brain and lung. KCTD12 plays a crucial role in regulating potassium channels, which are essential for maintaining electrical excitability of cells, particularly in the nervous system. Proper functioning of KCTD12 is vital for neuronal signaling and overall cellular homeostasis, making KCTD12 an important factor in understanding various neurological conditions. KCTD12 has been identified as a prognostic biomarker for gastrointestinal stromal tumors, highlighting KCTD12′s significance in cancer research and potential therapeutic applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
KCTD12 Antibody (F-6) References:
- Isolation from cochlea of a novel human intronless gene with predominant fetal expression. | Resendes, BL., et al. 2004. J Assoc Res Otolaryngol. 5: 185-202. PMID: 15357420
- Selection of common markers for bone marrow stromal cells from various bones using real-time RT-PCR: effects of passage number and donor age. | Igarashi, A., et al. 2007. Tissue Eng. 13: 2405-17. PMID: 17596118
- Pfetin as a prognostic biomarker of gastrointestinal stromal tumors revealed by proteomics. | Suehara, Y., et al. 2008. Clin Cancer Res. 14: 1707-17. PMID: 18347171
- Characterization and expression of a human KCTD1 gene containing the BTB domain, which mediates transcriptional repression and homomeric interactions. | Ding, XF., et al. 2008. DNA Cell Biol. 27: 257-65. PMID: 18358072
- Global protein-expression analysis of bone and soft tissue sarcomas. | Kawai, A., et al. 2008. Clin Orthop Relat Res. 466: 2099-106. PMID: 18535868
- The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. | Zollman, S., et al. 1994. Proc Natl Acad Sci U S A. 91: 10717-21. PMID: 7938017
- The POZ domain: a conserved protein-protein interaction motif. | Bardwell, VJ. and Treisman, R. 1994. Genes Dev. 8: 1664-77. PMID: 7958847
- Crystal structure of the BTB domain from PLZF. | Ahmad, KF., et al. 1998. Proc Natl Acad Sci U S A. 95: 12123-8. PMID: 9770450
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KCTD12 Antibody (F-6) | sc-271855 | 200 µg/ml | $316.00 | |||
KCTD12 Antibody (F-6): m-IgG Fc BP-HRP Bundle | sc-527301 | 200 µg Ab; 10 µg BP | $354.00 | |||
KCTD12 Antibody (F-6): m-IgG1 BP-HRP Bundle | sc-532674 | 200 µg Ab; 20 µg BP | $354.00 | |||
KCTD12 Antibody (F-6) AC | sc-271855 AC | 500 µg/ml, 25% agarose | $416.00 | |||
KCTD12 Antibody (F-6) HRP | sc-271855 HRP | 200 µg/ml | $316.00 | |||
KCTD12 Antibody (F-6) FITC | sc-271855 FITC | 200 µg/ml | $330.00 | |||
KCTD12 Antibody (F-6) PE | sc-271855 PE | 200 µg/ml | $343.00 | |||
KCTD12 Antibody (F-6) Alexa Fluor® 488 | sc-271855 AF488 | 200 µg/ml | $357.00 | |||
KCTD12 Antibody (F-6) Alexa Fluor® 546 | sc-271855 AF546 | 200 µg/ml | $357.00 | |||
KCTD12 Antibody (F-6) Alexa Fluor® 594 | sc-271855 AF594 | 200 µg/ml | $357.00 | |||
KCTD12 Antibody (F-6) Alexa Fluor® 647 | sc-271855 AF647 | 200 µg/ml | $357.00 | |||
KCTD12 Antibody (F-6) Alexa Fluor® 680 | sc-271855 AF680 | 200 µg/ml | $357.00 | |||
KCTD12 Antibody (F-6) Alexa Fluor® 790 | sc-271855 AF790 | 200 µg/ml | $357.00 | |||
KCTD12 (F-6) Neutralizing Peptide | sc-271855 P | 100 µg/0.5 ml | $68.00 |