Katanin p60 AL1 Antibody (E-5): sc-398801

Katanin p60 AL1 Antibody (E-5) is a mouse monoclonal IgG1 antibody that detects Katanin p60 AL1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Katanin p60 AL1 plays a crucial role in microtubule dynamics, specifically in the severing and disassembly of microtubules, which is essential for various cellular processes, including mitosis and the organization of the cytoskeleton. Katanin p60 AL1 is localized in the cytoplasm and is particularly important during cell division, as anti-Katanin p60 AL1 antibody (E-5) helps to regulate the mitotic spindle by severing microtubules, thereby facilitating the proper segregation of chromosomes. Katanin p60 AL1 is part of a larger complex that includes Katanin p80 B1, which targets the complex to the centrosome, ensuring that microtubule severing occurs at the right location within the cell. Understanding the function and dynamics of Katanin p60 AL1 is vital for elucidating the mechanisms of cell division and the maintenance of cellular architecture, making Katanin p60 AL1 (E-5) antibody an invaluable tool for researchers studying cytoskeletal organization and related cellular processes.

The preferred Katanin p60 AL1 antibody is Katanin p60 AL1 Antibody (A-10): sc-373814.