KAP3 Antibody (D-10): sc-374384
- KAP3 Antibody (D-10) is a mouse monoclonal IgG2a (lambda light chain) provided at 200 µg/ml
- specific for an epitope mapping between amino acids 761-787 at the C-terminus of KAP3 of human origin
- recommended for detection of KAP3A of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and porcine
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for KAP3 Antibody (D-10) for WB applications. This reagent is now offered in a bundle with KAP3 Antibody (D-10) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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KAP3 Antibody (D-10) is a mouse monoclonal IgG2a antibody that detects KAP3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KAP3, also known as SMAP in humans, plays a crucial role as an adaptor protein that facilitates the interaction between kinesin superfamily proteins and chromosome-associated proteins, which is essential for proper chromosome movement and stability during cell division. KAP3′s ability to form ternary complexes with human chromosome-associated polypeptide (HCAP) and kinesin II proteins underscores KAP3′s importance in the transport of membranous organelles and the maintenance of chromosomal integrity. Notably, KAP3 undergoes post-translational modifications, including tyrosine phosphorylation by v-Src, which can influence KAP3′s function and interactions, thereby impacting cellular processes such as mitosis and intracellular transport. Anti-KAP3 antibody (D-10) serves as an invaluable tool for researchers studying the dynamics of chromosome behavior and the molecular mechanisms underlying cellular transport processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KAP3 Antibody (D-10) | sc-374384 | 200 µg/ml | $322.00 | |||
KAP3 Antibody (D-10): m-IgGλ BP-HRP Bundle | sc-522718 | 200 µg Ab, 40 µg BP | $361.00 | |||
KAP3 (D-10) Neutralizing Peptide | sc-374384 P | 100 µg/0.5 ml | $69.00 |