KAP3 Antibody (B-4): sc-55599

KAP3 Antibody (B-4) is a mouse monoclonal IgG1 antibody that detects KAP3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KAP3, also known as SMAP in humans, plays a crucial role as an adaptor protein that facilitates interaction between kinesin superfamily proteins and chromosome-associated proteins, which is essential for proper chromosome movement during cell division. KAP3′s ability to form ternary complexes with human chromosome-associated polypeptide (HCAP) and kinesin II proteins underscores its importance in maintaining chromosomal stability and ensuring accurate segregation of chromosomes during mitosis. Additionally, KAP3 is subject to post-translational modifications, including tyrosine phosphorylation by v-Src, which can influence function and interactions, highlighting dynamic regulatory mechanisms that govern activity in cellular processes. Anti-KAP3 antibody (B-4) is an invaluable tool for researchers studying KAP3′s intricate roles in cellular transport and chromosomal dynamics, providing insights into molecular underpinnings of these critical biological functions.

The preferred KAP3 antibody is KAP3 Antibody (D-6): sc-55598.