JAKMIP2 Antibody (B-8): sc-393643
- JAKMIP2 Antibody (B-8) is a mouse monoclonal IgM κ provided at 200 µg/ml
- raised against amino acids 377-416 mapping within an internal region of JAKMIP2 of human origin
- recommended for detection of JAKMIP2 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for JAKMIP2 Antibody (B-8). This work is in progress.
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JAKMIP2 Antibody (B-8) is a mouse monoclonal IgM antibody that detects JAKMIP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). JAKMIP2, also known as NECC1, CTCL tumor antigen HD-CL-04, JAMIP2, or KIAA0555, is an 810 amino acid protein that plays a crucial role in cellular signaling and microtubule dynamics, particularly in neuroendocrine functions. JAKMIP2 is predominantly localized to the Golgi apparatus, which is essential for protein sorting and trafficking, thereby influencing various cellular processes such as secretion and signal transduction. Disruptions in JAKMIP2 activity can lead to significant implications in neuroendocrine signaling pathways and may contribute to the development of certain cancers. JAKMIP2 exists in three alternatively spliced isoforms, and the gene encoding JAKMIP2 is located on human chromosome 5q32, a region associated with various genetic disorders, including Cri du chat syndrome and therapy-related acute myelogenous leukemias. High expression of JAKMIP2 in the brain, along with moderate levels in the thymus, spleen, and lung, underscores JAKMIP2′s importance in both neurological and immune functions, making anti-JAKMIP2 antibody (B-8) a valuable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JAKMIP2 Antibody (B-8) | sc-393643 | 200 µg/ml | $322.00 |