JAK1 Antibody (73): sc-136225
- JAK1 Antibody (73) is a mouse monoclonal IgG2b κ, cited in 11 publications, provided at 50 µg/0.5 ml
- raised against amino acids 551-766 of JAK1 of human origin
- recommended for detection of JAK1 of mouse, rat, human and canine origin by WB, IP and IF
- See JAK1 (B-3): sc-376996 for JAK1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for JAK1 Antibody (73). This work is in progress.
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JAK1 Antibody (73) is a mouse monoclonal IgG2b antibody that detects JAK1 in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). JAK1, or Janus kinase 1, plays a crucial role in the signaling pathways of the immune system, particularly in the regulation of cellular functions downstream of activated cytokine receptors. JAK1 is primarily located in the cytoplasm, where JAK1 interacts with various cytokine receptors and transcription factors, facilitating the transmission of signals that lead to gene expression changes essential for immune responses. Proper localization of JAK1 is vital, as JAK1 ensures that the signaling cascade is initiated promptly upon cytokine binding, allowing for rapid cellular responses to immunological stimuli. Dysregulation of JAK1 activity can lead to impaired immune function or contribute to autoimmune diseases, making JAK1 a significant target for therapeutic intervention. Anti-JAK1 antibody (73) is an invaluable tool for researchers studying the JAK-Stat signaling pathway and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JAK1 Antibody (73) | sc-136225 | 50 µg/0.5 ml | $322.00 |