ISG15 Antibody (3C2): sc-130516
- ISG15 Antibody (3C2) is a Armenian hamster monoclonal IgG provided at 200 µg/ml
- raised against His-tagged recombinant ISG15 of mouse origin
- recommended for detection of ISG15 of mouse origin by WB, IP and IF
- See ISG15 (F-9): sc-166755 for ISG15 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ISG15 Antibody (3C2). This work is in progress.
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ISG15 Antibody (3C2) is an Armenian hamster monoclonal IgG antibody that detects ISG15 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-ISG15 antibody (3C2) is raised against His-tagged recombinant ISG15 of mouse origin. ISG15, a 15 kDa protein, plays a crucial role in the immune response by functioning as a ubiquitin-like modifier, conjugating to various intracellular target proteins, including JAK1 and MAPK3/ERK1, through a unique enzymatic pathway that is distinct from that of ubiquitin. This modification is vital for regulating protein stability and activity, thereby influencing key signaling pathways involved in immune responses. ISG15 (3C2) antibody exhibits specific chemotactic activity towards neutrophils, activating them to release eosinophil chemotactic factors, which further underscores its importance in orchestrating immune cell interactions. ISG15 is predominantly located in the cytoplasm and is expressed in muscle, epithelial, neuronal, and lymphoid cells, highlighting its diverse roles in various tissues. Anti-ISG15 antibody (3C2) is an essential tool for researchers studying the intricate mechanisms of immune modulation and cellular signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ISG15 Antibody (3C2) | sc-130516 | 200 µg/ml | $322.00 |