IRF-5 Antibody (D-10): sc-390365

IRF-5 Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects interferon regulatory factor 5 (IRF-5) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IRF-5 plays a crucial role in the immune response by acting as a transcription factor that regulates the expression of various cytokines and chemokines, which are essential for mediating inflammation and immune responses. IRF-5 is primarily located in the nucleus, where IRF-5 binds to specific DNA sequences to activate the transcription of interferon and interferon-inducible genes, thereby enhancing the host′s defense against viral infections. Nuclear localization of IRF-5 is vital, as nuclear localization allows for timely and effective regulation of immune responses, particularly during viral challenges. Additionally, IRF-5 interacts with other proteins, such as p53, which can influence IRF-5 activity and stability, further underscoring IRF-5′s importance in cellular signaling pathways. IRF-5 (D-10) antibody is an invaluable tool for researchers studying the intricate mechanisms of immune regulation and the role of IRF-5 in various diseases.

The preferred IRF-5 antibody is IRF-5 Antibody (10T1): sc-56714.