Date published: 2026-4-5

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IRF-4 Antibody (F-4): sc-48338

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Datasheets
  • IRF-4 Antibody (F-4) is a mouse monoclonal IgG2a κ IRF-4 antibody, cited in 16 publications, provided at 200 µg/ml
  • raised against amino acids 128-267 of IRF-4 of human origin
  • IRF-4 Antibody (F-4) is recommended for detection of IRF-4 of mouse, rat and human origin by WB, IP, IF and ELISA
  • Anti-IRF-4 Antibody (F-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • TransCruz reagent for Gel Supershift and ChIP applications (sc-48338 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for IRF-4 Antibody (F-4) for WB applications. These reagents are now offered in bundles with IRF-4 Antibody (F-4) (see ordering information below).
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IRF-4 Antibody (F-4) is a mouse monoclonal IgG2a kappa light chain antibody that detects IRF-4 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IRF-4 (F-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Interferon regulatory factor-4 (IRF-4) plays a crucial role in the immune system as a transcriptional activator that regulates the expression of genes involved in immune responses, particularly in lymphoid cells. IRF-4 is essential for the differentiation of T helper 2 cells and the development of plasma cells, which are vital for antibody production. IRF-4′s ability to bind to the interferon-stimulated response element (ISRE) of the major histocompatibility complex (MHC) class I promoter underscores IRF-4′s importance in modulating immune responses and maintaining immune homeostasis. Additionally, IRF-4 interacts with other proteins, such as PU.1, which further highlights IRF-4′s role in the regulation of gene expression within the immune system. This multifaceted involvement in immune regulation makes IRF-4 a significant target for research in immunology and related fields.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

IRF-4 Antibody (F-4)

sc-48338
200 µg/ml
$322.00

IRF-4 Antibody (F-4): m-IgG Fc BP-HRP Bundle

sc-525558
200 µg Ab; 10 µg BP
$361.00

IRF-4 Antibody (F-4): m-IgG2a BP-HRP Bundle

sc-546314
200 µg Ab; 10 µg BP
$361.00

IRF-4 Antibody (F-4) X

sc-48338 X
200 µg/0.1 ml
$322.00

IRF-4 Antibody (F-4) AC

sc-48338 AC
500 µg/ml, 25% agarose
$424.00

IRF-4 Antibody (F-4) HRP

sc-48338 HRP
200 µg/ml
$322.00

IRF-4 Antibody (F-4) FITC

sc-48338 FITC
200 µg/ml
$336.00

IRF-4 Antibody (F-4) PE

sc-48338 PE
200 µg/ml
$349.00

IRF-4 Antibody (F-4) Alexa Fluor® 488

sc-48338 AF488
200 µg/ml
$364.00

IRF-4 Antibody (F-4) Alexa Fluor® 546

sc-48338 AF546
200 µg/ml
$364.00

IRF-4 Antibody (F-4) Alexa Fluor® 594

sc-48338 AF594
200 µg/ml
$364.00

IRF-4 Antibody (F-4) Alexa Fluor® 647

sc-48338 AF647
200 µg/ml
$364.00

IRF-4 Antibody (F-4) Alexa Fluor® 680

sc-48338 AF680
200 µg/ml
$364.00

IRF-4 Antibody (F-4) Alexa Fluor® 790

sc-48338 AF790
200 µg/ml
$364.00

Hi, I am interested in purchasing IRF4 antibody (Human/ mouse) that binds N terminus of the protein, and I was wondering whether you have mapped the epitope for IRF4 F-4 (sc-48338) or do you have any product that you could recommend?

Asked by: Bahareh
Thank you for your question. Anti-IRF-4 Antibody (F-4): sc-48338 was raised against amino acids 128-267 of IRF-4 of human origin.
Answered by: Tech Support Europe
Date published: 2021-06-25

Can the TransCruz Reagent sc-48338 X be used in applications other than ChIP and EMSA?

Asked by: AbPolly
Thank you for your question. Yes, the X form of the antibody can be used in other applications such as Western Blot, IF and IHC. The dilution factor needs to be adjusted as the X form is ten times as concentrated as the standard antibody.
Answered by: Technical Service
Date published: 2017-01-27
  • y_2026, m_3, d_26, h_7CST
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Rated 5 out of 5 by from FACS stainingWe detected it by intracellular FACS staining in THP-1 cells.
Date published: 2024-05-14
Rated 1 out of 5 by from Zero starI bought this antibody twice, neither worked for IB, IP or IF. SC used to have goat IRF4 (M17) and mouse IRF4(MUM1p), both great for IP and IB. But they were discontinued and replaced with this garbage for no reason. It has been more and more antibodies from SC do not work, and you just waste your time and efforts to try them. So I am now switching to other companies.
Date published: 2019-09-18
Rated 5 out of 5 by from Great feature!The results of this antibody is really good and I really love it
Date published: 2018-01-05
Rated 3 out of 5 by from Good antibodyWorked well with western blotting at 1:500 dilution.
Date published: 2017-09-27
Rated 5 out of 5 by from greatThis antibody works really well in IF at 1:50 dilution.
Date published: 2017-08-23
Rated 5 out of 5 by from Used it in WBWe tested the Western blot, got a strong signal.good
Date published: 2017-04-05
Rated 5 out of 5 by from it works for mouse liver proteinThe antibody worked well to detect the protein in mouse liver tissue by western blotting.
Date published: 2017-03-28
Rated 5 out of 5 by from Excellent choice ab for detecting IRF-4 in WBGives clear distinct bands in NAMALWA and GA-10 whole cell lysate
Date published: 2016-12-29
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IRF-4 Antibody (F-4) is rated 4.4 out of 5 by 10.
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