IP6K2 Antibody (G-9): sc-373770
- IP6K2 Antibody (G-9) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 36-69 near the N-terminus of IP6K2 of human origin
- Anti-IP6K2 Antibody (G-9) is recommended for detection of IP6K2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine, bovine and porcine
- Anti-IP6K2 Antibody (G-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for IP6K2 Antibody (G-9) for WB and IHC(P) applications. These reagents are now offered in bundles with IP6K2 Antibody (G-9) (see ordering information below).
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IP6K2 Antibody (G-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects IP6K2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-IP6K2 antibody (G-9) is offered in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. IP6K2 plays a crucial role in cellular signaling by converting inositol hexakisphosphate (InsP6) into pyrophosphate inositol pentakisphosphate (PP-InsP5), which is essential for regulating calcium influx across the plasma membrane and subsequently influencing insulin exocytosis. This enzymatic activity links inositol phosphate metabolism to energy transfer processes within the cell, highlighting IP6K2′s significance in metabolic regulation and cellular communication. InsP6′s ability to inhibit serine/threonine protein phosphatases further underscores IP6K2′s importance in maintaining cellular homeostasis and signaling pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
IP6K2 Antibody (G-9) References:
- PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase. | Schell, MJ., et al. 1999. FEBS Lett. 461: 169-72. PMID: 10567691
- Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases. | Saiardi, A., et al. 1999. Curr Biol. 9: 1323-6. PMID: 10574768
- Inositol hexakisphosphate and beta-cell stimulus-secretion coupling. | Barker, CJ. and Berggren, PO. 1999. Anticancer Res. 19: 3737-41. PMID: 10625950
- Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor. | Voglmaier, SM., et al. 1996. Proc Natl Acad Sci U S A. 93: 4305-10. PMID: 8633060
- Identification and purification of diphosphoinositol pentakisphosphate kinase, which synthesizes the inositol pyrophosphate bis(diphospho)inositol tetrakisphosphate. | Huang, CF., et al. 1998. Biochemistry. 37: 14998-5004. PMID: 9778378
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IP6K2 Antibody (G-9) | sc-373770 | 200 µg/ml | $322.00 | |||
IP6K2 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-529558 | 200 µg Ab; 10 µg BP | $361.00 | |||
IP6K2 Antibody (G-9): m-IgGκ BP-HRP Bundle | sc-522492 | 200 µg Ab, 40 µg BP | $361.00 | |||
IP6K2 Antibody (G-9): m-IgG1 BP-HRP Bundle | sc-543578 | 200 µg Ab; 20 µg BP | $361.00 | |||
IP6K2 Antibody (G-9) AC | sc-373770 AC | 500 µg/ml, 25% agarose | $424.00 | |||
IP6K2 Antibody (G-9) HRP | sc-373770 HRP | 200 µg/ml | $322.00 | |||
IP6K2 Antibody (G-9) FITC | sc-373770 FITC | 200 µg/ml | $336.00 | |||
IP6K2 Antibody (G-9) PE | sc-373770 PE | 200 µg/ml | $349.00 | |||
IP6K2 Antibody (G-9) Alexa Fluor® 488 | sc-373770 AF488 | 200 µg/ml | $364.00 | |||
IP6K2 Antibody (G-9) Alexa Fluor® 546 | sc-373770 AF546 | 200 µg/ml | $364.00 | |||
IP6K2 Antibody (G-9) Alexa Fluor® 594 | sc-373770 AF594 | 200 µg/ml | $364.00 | |||
IP6K2 Antibody (G-9) Alexa Fluor® 647 | sc-373770 AF647 | 200 µg/ml | $364.00 | |||
IP6K2 Antibody (G-9) Alexa Fluor® 680 | sc-373770 AF680 | 200 µg/ml | $364.00 | |||
IP6K2 Antibody (G-9) Alexa Fluor® 790 | sc-373770 AF790 | 200 µg/ml | $364.00 | |||
IP6K2 (G-9) Neutralizing Peptide | sc-373770 P | 100 µg/0.5 ml | $69.00 |