Integrin β3/ITGB3/CD61 Antibody (B-7): sc-46655

Integrin β3 Antibody (B-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Integrin β3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Integrin β3 antibody (B-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Integrin β3 is a crucial component of integrin receptors, which are heterodimers formed by noncovalently associated transmembrane alpha and beta subunits. Integrin β3 mediates cell adhesion and signaling by interacting with ligands in the extracellular matrix, such as fibronectin, collagen, and vitronectin, as well as soluble ligands like fibrinogen. Such interactions enable integrin clustering and activation, triggering signaling pathways that influence cell growth, differentiation, migration, and apoptosis. Integrin β3′s role in facilitating these processes highlights its significance in maintaining cellular functions and tissue integrity, making Integrin β3 a valuable target for research in cell biology and therapeutic applications.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin β3/ITGB3/CD61 Antibody (B-7) has 29 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin β3/ITGB3/CD61 Antibody (B-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin β3/ITGB3/CD61 Antibody (B-7) Specifications

Alternate Product Name: Integrin β3

Product Clone Name: B-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 635-730

Epitope Target: Integrin β3

Epitope Species: human

Product Reactivity/Detection: Integrin β3

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 29 citations in various scientific publications

Available Conjugates/Forms for Integrin β3/ITGB3/CD61 Antibody (B-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Integrin αV/β3/CD51/CD61 antibody is Integrin αV/β3/CD51/CD61 Antibody (23C6): sc-7312.