Integrin β2/ITGB2/CD18 Antibody (H-7): sc-393140

Integrin β2 Antibody (H-7) is a mouse monoclonal IgG1 antibody that detects Integrin β2 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Integrin β2 is a crucial component of the integrin family, which consists of heterodimers formed by noncovalently associated transmembrane α and β subunits. Specifically, Integrin β2 pairs with different α subunits to form receptors that play a vital role in cell adhesion and signaling. Integrin β2 is predominantly located on the cell surface, where Integrin β2 interacts with extracellular matrix components and other cells, facilitating processes such as leukocyte migration and immune response. This localization is essential for proper immune system functioning, as Integrin β2 allows for adhesion of immune cells to sites of inflammation and injury, thereby promoting effective immune surveillance and response. Integrin β2 also participates in signaling pathways that regulate cell growth, differentiation, and apoptosis, making Integrin β2 a key player in both normal physiological processes and pathological conditions. Integrin β2′s ability to mediate these interactions underscores its importance in maintaining cellular homeostasis and responding to external stimuli.

The preferred Integrin β2/ITGB2/CD18 antibody is Integrin β2/ITGB2/CD18 Antibody (CTB104): sc-8420.