Integrin αE/ITGAE/CD103 Antibody (OX62): sc-53085

Integrin αE Antibody (OX62) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Integrin αE protein of mouse and rat origin by immunofluorescence (IF) and flow cytometry (FCM). Integrin αE, also known as ITGAE or CD103, plays a crucial role in the immune system by mediating the adhesion of T cells to epithelial cells, particularly in the gut, where anti-Integrin αE antibody (OX62) is essential for the retention of intraepithelial lymphocytes. This localization is vital as Integrin αE helps maintain the integrity of the epithelial barrier and contributes to immune surveillance and response in mucosal tissues. The interaction of Integrin αE with E-cadherin facilitates the formation of stable cell-cell contacts, which are important for tissue homeostasis and immune regulation. Integrin αE monoclonal antibody (OX62) is involved in signaling pathways that influence T cell activation and differentiation, making Integrin αE a key player in both innate and adaptive immunity. With specific binding capabilities and ability to mediate critical cellular interactions, Integrin αE (OX62) antibody serves as an invaluable tool for researchers studying immune responses, cell adhesion mechanisms, and the role of integrins in various biological processes.

The preferred Integrin αE/ITGAE/CD103 antibody is Integrin αE/ITGAE/CD103 Antibody (Ber-ACT8): sc-19981.