Integrin α6/ITGA6/CD49f Antibody (BQ16): sc-13542

Integrin α6 Antibody (BQ16) is a mouse monoclonal IgG1 kappa light chain antibody raised against the UM-UC-9 human bladder cancer cell line, designed to detect human Integrin α6 by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Integrin α6, also known as ITGA6 or CD49f, is a transmembrane protein predominantly located on the cell surface, where anti-Integrin α6 antibody (BQ16) plays a critical role in mediating cell adhesion to the extracellular matrix by interacting with laminin. This cell surface localization enables Integrin α6 to facilitate essential cellular processes such as signal transduction, migration, proliferation, and survival. As a member of the integrin family, Integrin α6 pairs primarily with β1 (ITGB1) and β4 (ITGB4) subunits to form heterodimers, contributing to the formation of over 20 different receptors that mediate diverse cell-matrix and cell-cell interactions. Dysregulation of Integrin α6 expression or function has been implicated in various pathological conditions, including cancer progression and metastasis, underscoring its importance as a target in biomedical research. Integrin α6 monoclonal antibody (BQ16) is available in non-conjugated form and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and Alexa Fluor® conjugates, offering versatility for various experimental applications. By accurately detecting Integrin α6, Integrin α6 (BQ16) antibody serves as a valuable tool for investigating the protein′s role in cellular adhesion, signaling pathways, and disease mechanisms.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin α6/ITGA6/CD49f Antibody (BQ16) has 18 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin α6/ITGA6/CD49f Antibody (BQ16) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin α6/ITGA6/CD49f Antibody (BQ16) Specifications

Alternate Product Name: Integrin α6

Product Clone Name: BQ16

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: Integrin α6

Epitope Species: human

Product Reactivity/Detection: Integrin α6

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 18 citations in various scientific publications

Available Conjugates/Forms for Integrin α6/ITGA6/CD49f Antibody (BQ16): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Integrin α6/ITGA6/CD49f antibody is Integrin α6/ITGA6/CD49f Antibody (GOH3): sc-19622.