Integrin α5/ITGA5/CD49e Antibody (JBS5): sc-59762

Integrin α5 Antibody (JBS5) is a mouse monoclonal IgG1 antibody that recognizes Integrin α5 in human and canine samples through immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Integrin α5 plays a crucial role in cell adhesion and is primarily located on the cell surface, where anti-Integrin α5 antibody (JBS5) detects heterodimers formed with the β1 subunit to create the α5β1 integrin receptor. This receptor is essential for binding to extracellular matrix components like fibronectin, which is vital for various cellular processes, including tissue repair and development. Integrin α5 on the cell surface facilitates the attachment of cells to the extracellular matrix, promoting cell migration and proliferation, which are critical during wound healing and embryogenesis. Furthermore, Integrin α5 interaction with fibronectin not only stabilizes cell adhesion but also initiates intracellular signaling pathways that influence cell behavior, making Integrin α5 a key player in maintaining tissue integrity and regulating cellular responses to environmental cues. Integrin α5 (JBS5) monoclonal antibody serves as an invaluable tool for researchers studying these fundamental processes in both human and canine models.

The preferred Integrin α5/ITGA5/CD49e antibody is Integrin α5/ITGA5/CD49e Antibody (P1D6): sc-13547.