Influenza A Virus Hemagglutinin Antibody (15A6) is a mouse monoclonal IgG2a light chain antibody that detects Influenza A Virus Hemagglutinin by enzyme-linked immunosorbent assay (ELISA). Influenza A Virus Hemagglutinin is a critical glycoprotein located on the surface of the virus, playing a vital role in viral infection of host cells. Influenza A Virus Hemagglutinin (15A6) antibody facilitates research on the initial attachment of the virus to host cells through binding to sialic acid residues on epithelial cell surfaces, which is essential for viral entry and replication. The structure of hemagglutinin undergoes conformational changes upon binding to host cells, triggering membrane fusion and allowing viral RNA entry. This process is crucial for influenza pathogenesis, making anti-Influenza A Virus Hemagglutinin antibody (15A6) significant for understanding viral infection mechanisms and developing effective vaccines and antiviral therapies. Influenza A Virus Hemagglutinin (15A6) monoclonal antibody serves as an invaluable tool for researchers investigating influenza virus infections and immune responses to these pathogens.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Influenza A Virus Hemagglutinin Antibody (15A6) References:
- Role of influenza A virus hemagglutinin in neurovirulence for mammalians. | Mori, I., et al. 2002. Med Microbiol Immunol. 191: 1-4. PMID: 12137193
- Receptor binding and pH stability - how influenza A virus hemagglutinin affects host-specific virus infection. | Mair, CM., et al. 2014. Biochim Biophys Acta. 1838: 1153-68. PMID: 24161712
- High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution. | Wu, NC., et al. 2014. Sci Rep. 4: 4942. PMID: 24820965
- Biogenesis of influenza a virus hemagglutinin cross-protective stem epitopes. | Magadán, JG., et al. 2014. PLoS Pathog. 10: e1004204. PMID: 24945804
- Subtype-specific structural constraints in the evolution of influenza A virus hemagglutinin genes. | Gultyaev, AP., et al. 2016. Sci Rep. 6: 38892. PMID: 27966593
- Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit. | Altman, MO., et al. 2019. mBio. 10: PMID: 30940704
- Drivers of recombinant soluble influenza A virus hemagglutinin and neuraminidase expression in mammalian cells. | van der Woude, R., et al. 2020. Protein Sci. 29: 1975-1982. PMID: 32710576
- Influenza A Virus Hemagglutinin Trimer, Head and Stem Proteins Identify and Quantify Different Hemagglutinin-Specific B Cell Subsets in Humans. | Aartse, A., et al. 2021. Vaccines (Basel). 9: PMID: 34358138
- The Cytoplasmic Tail of Influenza A Virus Hemagglutinin and Membrane Lipid Composition Change the Mode of M1 Protein Association with the Lipid Bilayer. | Kordyukova, LV., et al. 2021. Membranes (Basel). 11: PMID: 34677538
- The evolutionary potential of influenza A virus hemagglutinin is highly constrained by epistatic interactions with neuraminidase. | Liu, T., et al. 2022. Cell Host Microbe. 30: 1363-1369.e4. PMID: 36150395