IL-3Rα Antibody (6H6 BOT): sc-80651

IL-3Rα Antibody (6H6 BOT) is a mouse monoclonal IgG1 antibody that detects IL-3Rα in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). IL-3Rα, or interleukin-3 receptor alpha, plays a crucial role in the immune system by serving as the specific binding site for interleukin-3, a cytokine that promotes the growth and differentiation of hematopoietic cells. IL-3Rα is primarily located on the surface of hematopoietic progenitor cells, where IL-3Rα facilitates the activation of downstream signaling pathways essential for cell survival and proliferation. The interaction between IL-3 and IL-3Rα is vital for the maintenance of normal blood cell production and immune responses, making IL-3Rα a significant target for therapeutic interventions in conditions such as leukemia and other hematological disorders. Notably, the IL-3 receptor complex also includes the common β subunit, which is shared with the receptors for IL-5 and GM-CSF, highlighting the interconnectedness of these signaling pathways in regulating hematopoiesis. Anti-IL-3Rα antibody (6H6 BOT) is an invaluable tool for researchers studying these critical processes in human health and disease.

The preferred IL-3Rα antibody is IL-3Rα Antibody (S-12): sc-455.