IL-26 Antibody (LL07): sc-80523

IL-26 Antibody (LL07) is a mouse monoclonal IgG2b antibody that detects IL-26 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-IL-26 antibody (LL07) is available as a non-conjugated format. IL-26, a member of the interleukin family, plays a crucial role in immune response, particularly in regulating inflammation and activating T cells. IL-26 is primarily secreted by activated T cells and has been implicated in various inflammatory diseases, making IL-26 an important target for therapeutic intervention. IL-26 interacts with specific receptors on target cells, leading to the activation of signaling pathways that promote pro-inflammatory cytokine expression. Understanding IL-26 function and interactions is vital for developing strategies to modulate immune responses in conditions such as autoimmune diseases and chronic inflammation.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

IL-26 Antibody (LL07) References:

1. Cutting edge: immune cells as sources and targets of the IL-10 family members?  |  Wolk, K., et al. 2002. J Immunol. 168: 5397-402. PMID: 12023331
2. IL-10 subfamily members: IL-19, IL-20, IL-22, IL-24 and IL-26.  |  Conti, P., et al. 2003. Immunol Lett. 88: 171-4. PMID: 12941475
3. Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.  |  Sheikh, F., et al. 2004. J Immunol. 172: 2006-10. PMID: 14764663
4. Interleukin-26.  |  Fickenscher, H. and Pirzer, H. 2004. Int Immunopharmacol. 4: 609-13. PMID: 15120646
5. The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.  |  Donnelly, RP., et al. 2004. J Leukoc Biol. 76: 314-21. PMID: 15123776
6. The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains.  |  Hör, S., et al. 2004. J Biol Chem. 279: 33343-51. PMID: 15178681
7. IL-19 induced Th2 cytokines and was up-regulated in asthma patients.  |  Liao, SC., et al. 2004. J Immunol. 173: 6712-8. PMID: 15557163
8. Structural studies of the interleukin-19 subfamily of cytokines.  |  Zdanov, A. 2006. Vitam Horm. 74: 61-76. PMID: 17027511
9. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.  |  Sa, SM., et al. 2007. J Immunol. 178: 2229-40. PMID: 17277128