IL-13Rα1 Antibody (GM-1E7): sc-101382

IL-13Rα1 Antibody (GM-1E7) is a mouse monoclonal IgG1 antibody that detects Interleukin-13 receptor alpha 1 (IL-13Rα1) in human samples through applications such as immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IL-13Rα1 plays a pivotal role in mediating the effects of the Th2 cytokine Interleukin-13, which is crucial for regulating immune responses, particularly in allergic reactions and asthma. IL-13Rα1 exists as a heterodimer with IL-4Rα, forming a functional signaling complex that activates downstream pathways essential for B cell differentiation and T cell responses. IL-13Rα1 is predominantly found in immune cells such as B cells, monocytes, and T cells, highlighting its importance in orchestrating immune responses. Understanding IL-13Rα1 structure and function is vital, as IL-13Rα1 not only facilitates IL-13 signaling but also plays a role in the pathophysiology of allergic diseases. Anti-IL-13Rα1 antibody (GM-1E7) is an invaluable tool for researchers investigating the mechanisms of IL-13 signaling and its implications in various immune-related conditions.

The preferred IL-13Rα1 antibody is IL-13Rα1 Antibody (D-2): sc-398831.