IGF-I Antibody (AT6F8): sc-517407
- IGF-I Antibody (AT6F8) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 100 µg/ml
- raised against a recombinant protein corresponding to amino acids 49-118 of IGF-I of human origin
- recommended for detection of IGF-I of human origin by WB and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IGF-I Antibody (AT6F8). This work is in progress.
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IGF-I Antibody (AT6F8) is a mouse monoclonal IgG2b antibody that detects insulin-like growth factor I (IGF-I) in human samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). IGF-I is a crucial peptide that plays a significant role in various physiological processes, including the stimulation of vascular smooth muscle cell growth and the regulation of renal function, growth, and tissue repair. Notably, IGF-I is also essential for bone formation and resorption, highlighting its importance in maintaining skeletal health. The activity of IGF-I is intricately modulated by a family of six circulating IGF-binding proteins (IGFBP1-6), which help regulate IGF-I availability and biological effects. Furthermore, IGF-I interacts with IGF-IR receptor, which is structurally similar to the insulin receptor, consisting of two extracellular alpha chains and two beta chains that transmit signals within the cell. IGF-IR receptor′s proper functioning is vital for mediating the diverse effects of IGF-I, including IGF-I influence on insulin sensitivity and glucose uptake, making IGF-I a key player in metabolic regulation. Anti-IGF-I antibody (AT6F8) is an invaluable tool for researchers investigating the multifaceted roles of IGF-I in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IGF-I Antibody (AT6F8) | sc-517407 | 100 µg/ml | $316.00 |