IFI-16 Antibody (D-1): sc-166504
- IFI-16 Antibody (D-1) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 712-729 at the C-terminus of IFI-16 of human origin
- recommended for detection of IFI-16 of human origin by WB, IP, IF, IHC(P) and ELISA
- See IFI-16 (1G7): sc-8023 for IFI-16 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP is the preferred secondary detection reagent for IFI-16 Antibody (D-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with IFI-16 Antibody (D-1) (see ordering information below).
IFI-16 Antibody (D-1) is a mouse monoclonal IgG2b antibody that detects IFI-16 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). IFI-16 plays a significant role in immune response, particularly in viral DNA recognition, which is essential for initiating appropriate immune reactions. IFI-16 is primarily localized in the nucleus, functioning as a transcriptional regulator and participating in gene expression modulation in response to interferon signaling. Nuclear localization of IFI-16 enables interaction with various transcription factors and chromatin, influencing expression of genes critical for immune defense. IFI-16 forms complexes with other proteins, such as myeloid cell nuclear differentiation antigen (MNDA), further highlighting IFI-16′s importance in immune response regulation. Interferon-gamma induction of IFI-16 in certain cell types emphasizes IFI-16′s role in adaptive immune response, making IFI-16 a valuable target for immunology research and potential therapeutic applications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFI-16 Antibody (D-1) | sc-166504 | 200 µg/ml | $316.00 | |||
IFI-16 Antibody (D-1): m-IgG2b BP-HRP Bundle | sc-548520 | 200 µg Ab; 10 µg BP | $354.00 | |||
IFI-16 (D-1) Neutralizing Peptide | sc-166504 P | 100 µg/0.5 ml | $68.00 |