Id2 Antibody (2457C5a): sc-81298
- Id2 Antibody (2457C5a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to a region near the N-terminus of Id2 of human origin
- recommended for detection of Id2 of human origin by WB and IP
- See Id2 (E-7): sc-398104 for Id2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Id2 Antibody (2457C5a). This work is in progress.
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Id2 Antibody (2457C5a) is a mouse monoclonal IgG1 antibody that detects Id2 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Id2 is a member of the Id family of basic helix-loop-helix (bHLH) proteins, which play a crucial role in regulating cell differentiation and proliferation. Id2 (2457C5a) antibody recognizes a protein known to inhibit the DNA binding activity of class A and B bHLH proteins, thereby preventing the transcription of genes necessary for muscle differentiation. This function is particularly important as Id2 allows for the regulation of muscle-specific gene expression during the cell cycle. Under conditions that promote muscle cell differentiation, Id2 levels decrease, enabling the formation of active heterodimers with proteins such as Myo D and myogenin, which are essential for initiating myogenic differentiation. Furthermore, Id2 expression is tightly regulated by growth factors, and studies have shown that reducing Id2 mRNA levels can delay the reentry of quiescent cells into the cell cycle following growth factor stimulation. This highlights the significance of Id2 not only in muscle development but also in broader cellular processes, making anti-Id2 antibody (2457C5a) a valuable tool for researchers studying these critical pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Id2 Antibody (2457C5a) | sc-81298 | 100 µg/ml | $333.00 |