HYLS1 Antibody (D-9): sc-376721
- HYLS1 Antibody (D-9) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 211-243 within an internal region of HYLS1 of human origin
- recommended for detection of HYLS1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HYLS1 Antibody (D-9) for WB applications. These reagents are now offered in bundles with HYLS1 Antibody (D-9) (see ordering information below).
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SEE ALSO...
HYLS1 Antibody (D-9) is a mouse monoclonal IgG2a antibody that detects HYLS1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HYLS1 is a highly conserved protein crucial for the formation of cilia, which are essential for various cellular functions, including signaling pathways and cellular motility. The proper assembly and function of cilia are vital for normal embryonic development and tissue homeostasis, as defects in cilia can lead to a range of developmental disorders and diseases, including hydrolethalus syndrome, characterized by severe malformations such as hydrocephaly and absent midline structures in the brain. The gene encoding HYLS1 is located on human chromosome 11, a region known for its density of gene and disease associations, which underscores the importance of HYLS1 in both normal physiology and disease states. Additionally, the chromosome 11 encoded Atm gene plays a significant role in regulating cell cycle arrest and apoptosis in response to DNA damage, with mutations in Atm leading to ataxia-telangiectasia, further highlighting the interconnectedness of these genetic factors in cellular health. HYLS1 (D-9) antibody is an invaluable tool for researchers studying cilia-related functions and associated pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HYLS1 Antibody (D-9) | sc-376721 | 200 µg/ml | $322.00 | |||
HYLS1 Antibody (D-9): m-IgG Fc BP-HRP Bundle | sc-538001 | 200 µg Ab; 10 µg BP | $361.00 | |||
HYLS1 Antibody (D-9): m-IgGκ BP-HRP Bundle | sc-535509 | 200 µg Ab; 40 µg BP | $361.00 | |||
HYLS1 Antibody (D-9): m-IgG2a BP-HRP Bundle | sc-548177 | 200 µg Ab; 10 µg BP | $361.00 | |||
HYLS1 (D-9) Neutralizing Peptide | sc-376721 P | 100 µg/0.5 ml | $69.00 |