HTLV-1 p24 Antibody (6G9): sc-53891
- HTLV-1 p24 Antibody (6G9) is a mouse monoclonal IgG1 κ HTLV-1 p24 antibody, cited in 6 publications, provided at 200 µg/ml
- raised against HTLV-I infected cells of HTLV-1 origin
- HTLV-1 p24 Antibody (6G9) is recommended for detection of HTLV-1 by WB, IP and IF
- Anti-HTLV-1 p24 Antibody (6G9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HTLV-1 p24 Antibody (6G9) for WB applications. These reagents are now offered in bundles with HTLV-1 p24 Antibody (6G9) (see ordering information below).
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HTLV-1 p24 Antibody (6G9) is a mouse monoclonal IgG1 kappa light chain antibody that detects HTLV-1 p24 protein of HTLV-1 origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). HTLV-1 p24 (6G9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HTLV-1 p24 protein plays a crucial role in the viral life cycle as a major structural component of the virus′s core, which is essential for the assembly and release of new viral particles. Understanding p24 function is important because p24 not only aids in virus identification but also serves as a target for therapeutic interventions aimed at preventing the progression of diseases associated with HTLV-1, such as T cell leukemia and lymphoma. The human T-lymphotropic virus (HTLV) is a single-stranded RNA retrovirus linked to various health issues, including HTLV-1-associated myelopathy and potential links to other demyelinating diseases. Transmission of HTLV-1 occurs through sexual contact, childbirth, and exposure to contaminated blood, making p24 detection critical for public health monitoring and intervention strategies. Additionally, the differential antibody response to p19 gag can help distinguish between HTLV-1 and HTLV-2, highlighting HTLV-1 p24 (6G9) monoclonal antibody significance in both research and clinical settings.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HTLV-1 p24 Antibody (6G9) References:
- Envelope is a major viral determinant of the distinct in vitro cellular transformation tropism of human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2. | Xie, L. and Green, PL. 2005. J Virol. 79: 14536-45. PMID: 16282453
- Human T lymphotropic virus types I and II western blot seroindeterminate status and its association with exposure to prototype HTLV-I. | Yao, K., et al. 2006. J Infect Dis. 193: 427-37. PMID: 16388491
- Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo. | Hiraragi, H., et al. 2006. J Virol. 80: 3469-76. PMID: 16537614
- Human T-cell leukemia virus (HTLV) in the United Kingdom. | Greaves, MF., et al. 1984. Int J Cancer. 33: 795-806. PMID: 6329969
- Production and characterization of a monoclonal antibody directed against HTLV-1 p19: use in a specific capture enzyme immunoassay. | Ebersold, A., et al. 1993. Hybridoma. 12: 185-95. PMID: 7686136
- [Molecular characterization of human T-cell lymphotrophic virus type II]. | Takahashi, H. 1993. Hokkaido Igaku Zasshi. 68: 485-95. PMID: 8340046
- Assessment of a new immunoassay for serological confirmation and discrimination of human T-cell lymphotropic virus infections. | Zrein, M., et al. 1998. Clin Diagn Lab Immunol. 5: 45-9. PMID: 9455879
- Differential antibody responsiveness to p19 gag results in serological discrimination between human T lymphotropic virus type I and type II. | Lal, RB., et al. 1991. J Med Virol. 35: 232-6. PMID: 1687064
- Substrates and inhibitors of human T-cell leukemia virus type I protease. | Ding, YS., et al. 1998. Biochemistry. 37: 17514-8. PMID: 9860866
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HTLV-1 p24 Antibody (6G9) | sc-53891 | 200 µg/ml | $322.00 | |||
HTLV-1 p24 Antibody (6G9): m-IgG Fc BP-HRP Bundle | sc-528585 | 200 µg Ab; 10 µg BP | $361.00 | |||
HTLV-1 p24 Antibody (6G9): m-IgGκ BP-HRP Bundle | sc-520997 | 200 µg Ab, 40 µg BP | $361.00 | |||
HTLV-1 p24 Antibody (6G9): m-IgG1 BP-HRP Bundle | sc-543009 | 200 µg Ab; 20 µg BP | $361.00 | |||
HTLV-1 p24 Antibody (6G9) AC | sc-53891 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HTLV-1 p24 Antibody (6G9) HRP | sc-53891 HRP | 200 µg/ml | $322.00 | |||
HTLV-1 p24 Antibody (6G9) FITC | sc-53891 FITC | 200 µg/ml | $336.00 | |||
HTLV-1 p24 Antibody (6G9) PE | sc-53891 PE | 200 µg/ml | $349.00 | |||
HTLV-1 p24 Antibody (6G9) Alexa Fluor® 488 | sc-53891 AF488 | 200 µg/ml | $364.00 | |||
HTLV-1 p24 Antibody (6G9) Alexa Fluor® 546 | sc-53891 AF546 | 200 µg/ml | $364.00 | |||
HTLV-1 p24 Antibody (6G9) Alexa Fluor® 594 | sc-53891 AF594 | 200 µg/ml | $364.00 | |||
HTLV-1 p24 Antibody (6G9) Alexa Fluor® 647 | sc-53891 AF647 | 200 µg/ml | $364.00 | |||
HTLV-1 p24 Antibody (6G9) Alexa Fluor® 680 | sc-53891 AF680 | 200 µg/ml | $364.00 | |||
HTLV-1 p24 Antibody (6G9) Alexa Fluor® 790 | sc-53891 AF790 | 200 µg/ml | $364.00 |