HPRT Antibody (B-11): sc-393901
- HPRT Antibody (B-11) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 16-39 near the N-terminus of HPRT of human origin
- recommended for detection of HPRT of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, bovine and porcine
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HPRT Antibody (B-11) for WB applications. These reagents are now offered in bundles with HPRT Antibody (B-11) (see ordering information below).
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SEE ALSO...
HPRT Antibody (B-11) is a mouse monoclonal IgG1 antibody that detects HPRT (hypoxanthine phosphoribosyltransferase 1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HPRT is a crucial cytoplasmic protein composed of 218 amino acids and belongs to the purine/pyrimidine phosphoribosyltransferase family, playing a vital role in purine metabolism as a purine salvage enzyme. HPRT catalyzes the conversion of hypoxanthine and guanine into their respective mononucleotides, inosine monophosphate and guanosine monophosphate, thereby facilitating the recycling of purines, which are essential for DNA and RNA synthesis. HPRT exists as a homotetramer and requires two magnesium ions as cofactors for enzymatic activity. Deficiencies in HPRT can lead to serious metabolic disorders, including gout and Lesch-Nyhan syndrome, highlighting HPRT′s importance in maintaining purine homeostasis. Anti-HPRT antibody (B-11) serves as an invaluable tool for researchers studying these conditions and the broader implications of purine metabolism in cellular function and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HPRT Antibody (B-11) | sc-393901 | 200 µg/ml | $322.00 | |||
HPRT Antibody (B-11): m-IgG Fc BP-HRP Bundle | sc-538334 | 200 µg Ab; 10 µg BP | $361.00 | |||
HPRT Antibody (B-11): m-IgGκ BP-HRP Bundle | sc-535923 | 200 µg Ab; 40 µg BP | $361.00 | |||
HPRT Antibody (B-11): m-IgG1 BP-HRP Bundle | sc-545649 | 200 µg Ab; 20 µg BP | $361.00 | |||
HPRT (B-11) Neutralizing Peptide | sc-393901 P | 100 µg/0.5 ml | $69.00 |