HoxB4 Antibody (C-10): sc-271083
- HoxB4 Antibody (C-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 21-47 near the N-terminus of HoxB4 of human origin
- recommended for detection of HoxB4 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- TransCruz reagent for ChIP application (sc-271083 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HoxB4 Antibody (C-10) for WB applications. These reagents are now offered in bundles with HoxB4 Antibody (C-10) (see ordering information below).
HoxB4 Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects HoxB4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HoxB4 is a crucial nuclear phosphoprotein encoded by the HOXB4 gene, which plays a significant role in regulating hematopoietic stem cell dynamics, specifically the balance between stem cell renewal and differentiation. This regulation is vital for maintaining proper blood cell development and ensuring a healthy hematopoietic system. HoxB4′s function is intricately linked to interactions with transcription factors such as USF-1 and USF-2, which modulate expression in response to cytokines that promote either self-renewal or differentiation of stem cells. Additionally, HoxB4 influences the cell cycle by increasing cyclin D1 levels and down-regulating c-Myc expression, thereby integrating signals that govern cellular proliferation and differentiation. Expression of HoxB4 is notably observed in developing hair follicles and in cell lines such as K-562 and HL-60, highlighting importance in both developmental biology and cancer research. Anti-HoxB4 antibody (C-10) is an essential tool for researchers investigating the mechanisms of stem cell biology and the regulatory networks involved in hematopoiesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HoxB4 Antibody (C-10) | sc-271083 | 200 µg/ml | $316.00 | |||
HoxB4 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-537567 | 200 µg Ab; 10 µg BP | $354.00 | |||
HoxB4 Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-534867 | 200 µg Ab; 40 µg BP | $354.00 | |||
HoxB4 Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-545233 | 200 µg Ab; 20 µg BP | $354.00 | |||
HoxB4 (C-10) Neutralizing Peptide | sc-271083 P | 100 µg/0.5 ml | $68.00 | |||
HoxB4 Antibody (C-10) X | sc-271083 X | 200 µg/0.1 ml | $316.00 |