Date published: 2026-5-10

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HMG-2L1 Antibody (D-1): sc-166828

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Datasheets
  • HMG-2L1 Antibody (D-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 409-587 mapping near the C-terminus of HMG-2L1 of human origin
  • recommended for detection of HMG-2L1 of mouse, rat and human origin by WB, IP, IF and ELISA
  • TransCruz reagent for ChIP application (sc-166828 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for HMG-2L1 Antibody (D-1) for WB applications. These reagents are now offered in bundles with HMG-2L1 Antibody (D-1) (see ordering information below).
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    HMG-2L1 Antibody (D-1) is a mouse monoclonal IgG1 antibody that detects HMG-2L1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HMG-2L1, also known as High mobility group protein 2-like 1 or HMGBCG, is a crucial member of the high mobility group chromosomal protein superfamily, characterized by its single HMG box DNA binding domain, which allows HMG-2L1 to interact with AT-rich DNA sequences. This interaction facilitates the bending and unwinding of DNA, thereby influencing the overall architecture of chromatin and playing a significant role in transcriptional regulation. HMG-2L1 is predominantly localized in the nucleus, where HMG-2L1 may collaborate with other transcription factors, such as Oct-2 and members of the NFkB family, to modulate gene expression. The ability of HMG-2L1 to bind DNA without an acidic C-terminal tail distinguishes HMG-2L1 from other HMG proteins, highlighting unique functional properties in cellular processes. With versatile applications and a critical role in gene regulation, anti-HMG-2L1 antibody (D-1) serves as an essential tool for researchers studying chromatin dynamics and transcriptional control.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    HMG-2L1 Antibody (D-1)

    sc-166828
    200 µg/ml
    $322.00

    HMG-2L1 Antibody (D-1): m-IgG Fc BP-HRP Bundle

    sc-540165
    200 µg Ab; 10 µg BP
    $361.00

    HMG-2L1 Antibody (D-1): m-IgG1 BP-HRP Bundle

    sc-541943
    200 µg Ab; 20 µg BP
    $361.00

    HMG-2L1 Antibody (D-1) X

    sc-166828 X
    200 µg/0.1 ml
    $322.00

    When should the TransCruz reagent sc-166828 X be used instead of the standard form sc-166828?

    Asked by: Germaine
    Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Works great for western blotting with mouse HMGWorks great for western blotting with mouse HMG-2L1 transfected lysates. -SCBT QC
    Date published: 2015-06-19
    Rated 5 out of 5 by from Superb immunofluorescence nuclear stainingSuperb immunofluorescence nuclear staining in formalin-fixed HepG2 cells. -SCBT QC
    Date published: 2015-04-01
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    HMG-2L1 Antibody (D-1) is rated 5.0 out of 5 by 2.
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